An Observational Multicenter Cross-sectional Study of Patients With Uncontrolled Severe Asthma in Russia

What this Trial Is About

Researchers are conducting an observational multicenter cross-sectional study involving 5,000 adult patients with uncontrolled severe asthma (SA) across approximately 50 outpatient centers in Russia. The study aims to describe the characteristics of patients with uncontrolled SA not receiving biologic treatments, addressing the lack of unified monitoring and epidemiological data for this population in Russia. This research is important to better understand the clinical and demographic features, treatment patterns, and outcomes of SA across different regions with diverse populations and environments. This non-interventional study involves only one visit per participant to collect demographic and clinical data without altering routine medical care or adding diagnostic or therapeutic procedures beyond standard practice. Patients receiving biologic therapies are excluded, focusing on those treated with standard care such as inhaled corticosteroids, long-acting bronchodilators, and systemic corticosteroids. The study will evaluate the use of routine therapies, patterns of oral corticosteroid prescriptions, and associated clinical characteristics including comorbidities and biomarkers. Participants will provide data from their medical records covering at least 52 weeks prior to inclusion, allowing researchers to analyze treatment changes, exacerbation rates, lung function, and healthcare resource use retrospectively. The study will collect information on demographics, asthma control scores, eosinophil counts, immunoglobulin E levels, and other clinical measures. Data collection spans from June 2024 to June 2027, with no interventions or additional monitoring beyond routine care, offering a comprehensive profile of uncontrolled SA in Russia.

Clinical and demOgRaphic Features of Patients With Uncontrolled Severe Asthma in Russia (CORSAR)