Actively Recruiting
the Clinical Effect of Nd: YAG Laser Assisted Periodontal Initial Therapy in Patients With Moderate to Severe Periodontitis
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2024-09-20
22
Participants Needed
1
Research Sites
16 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if Neodymium-Doped Yttrium Aluminum Garnet（Nd: YAG） Laser-assisted non-surgical periodontal treatment is effective in treating stage II/III periodontitis. It will also evaluate the safety and impact of the laser treatment. The main questions it aims to answer are: 1. Does Nd: YAG Laser treatment reduce probing depth, gingival inflammation, and clinical attachment loss more effectively than standard Scaling and root planing(SRP) therapy alone? 2. What changes in inflammatory markers and oxidative stress levels occur when patients receive laser-assisted therapy? Researchers will compare Nd: YAG Laser treatment to standard periodontal therapy alone to determine the effectiveness of the laser treatment. Participants will: 1. Receive Nd: YAG Laser assisted therapy on one side of their mouth and standard therapy on the other side. 2. Visit the clinic at baseline, 6 weeks, and 3 months for follow-up assessments and tests. 3. Provide samples and have measurements taken of periodontal health and biomarkers of inflammation and oxidative stress.
CONDITIONS
Official Title
the Clinical Effect of Nd: YAG Laser Assisted Periodontal Initial Therapy in Patients With Moderate to Severe Periodontitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 65 years, with no gender restrictions.
- Diagnosed with stage II or III periodontitis according to the 2018 Classification of Periodontal and Peri-Implant Diseases and Conditions.
- At least one tooth in each of the four oral quadrants must have one site with probing depth 65 mm, clinical attachment loss 62 mm, and bleeding on probing.
- Participants must provide informed consent and sign the informed consent form.
You will not qualify if you...
- Fewer than 20 remaining teeth or a significant difference in the number of remaining teeth between the left and right sides of the mouth.
- Periodontal treatment within the past six months or current orthodontic treatment.
- Presence of systemic diseases that could affect periodontal treatment results.
- Severe infections, malignancies, or other major diseases affecting overall health.
- Pregnant or breastfeeding women.
- History of smoking.
- Inability to comply with or complete periodontal treatment.
AI-Screening
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Trial Site Locations
Total: 1 location
1
The Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310009
Actively Recruiting
Research Team
J
Jingyi Tan, Doctor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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