Actively Recruiting

Phase Not Applicable
Age: 19Years - 75Years
All Genders
Healthy Volunteers
NCT06334562

The Clinical Effect of Sugammadex Sodium (Domestic) for Antagonizing Neuromuscular Blockade After Thoracic Surgery

Led by The Fourth Affiliated Hospital of Zhejiang University School of Medicine · Updated on 2025-02-17

80

Participants Needed

1

Research Sites

82 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to compare the use of sugammadex (domestic) and neostigmine for antagonism after thoracic surgery, and observe the effect of sugammadex (domestic) on neuromuscular blockade antagonism after thoracic surgery, in order to provide a basis for optimizing the use of muscle relaxants and their antagonists during anesthesia.

CONDITIONS

Official Title

The Clinical Effect of Sugammadex Sodium (Domestic) for Antagonizing Neuromuscular Blockade After Thoracic Surgery

Who Can Participate

Age: 19Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients undergoing elective lung surgery under general anesthesia requiring endotracheal intubation
  • Age over 18 years, any gender
  • American Society of Anesthesiologists (ASA) physical status level I to III
  • Use of rocuronium bromide for neuromuscular blockade
  • Voluntary participation in the trial
Not Eligible

You will not qualify if you...

  • Refusal to participate in the trial
  • Family history of malignant hyperthermia or allergies to sodium sulbactam, neostigmine ingredients, or anesthesia drugs
  • Presence of tracheal malformations or suspected difficult airway
  • Coagulation disorders, severe liver or kidney dysfunction, or severe lung disease
  • Patients not extubated and sent to ward or ICU after surgery
  • Any other factors deemed unfavorable by researchers for participation

AI-Screening

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Trial Site Locations

Total: 1 location

1

The Fourth Affiliated Hospital of Zhejiang University School of Medicine

Yiwu, Zhejiang, China, 322000

Actively Recruiting

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Research Team

J

JianHong Xu

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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The Clinical Effect of Sugammadex Sodium (Domestic) for Antagonizing Neuromuscular Blockade After Thoracic Surgery | DecenTrialz