Evaluating Intervertebral Disc Release Compared to Ponte Osteotomy for Lenke 5 Adolescent Idiopathic Scoliosis in Patients Aged 10 to 18

What this Trial Is About

This research aims to evaluate the clinical effectiveness of intervertebral disc release IDR in treating adolescents aged 10 to 18 with Lenke 5 type adolescent idiopathic scoliosis AIS. The study compares IDR with Ponte osteotomy to assess improvements in vertebral rotation correction, coronal curve angles, blood loss, hospital stay length, and adverse events. The trial focuses on providing robust clinical evidence to enhance treatment strategies for this specific scoliosis type and potentially for AIS overall. Participants will be randomly assigned to one of two groups the IDR group, which receives intervertebral disc release following Ponte osteotomy at certain vertebral levels, or the PO group, which receives only Ponte osteotomy. Both procedures involve posterior instrumentation, fusion, and corrective maneuvers such as rod rotation and segmental derotation. The IDR technique includes incising and removing disc material to allow better derotation and reduce fusion levels. During the study, participants will undergo various evaluations including measurements of axial vertebral rotation correction, lumbar curve, vertebral tilt, and other radiographic parameters at multiple time points before surgery and up to three years post-surgery. Clinical assessments will include blood loss, transfusion rates, hospital stay length, infection rates, nerve damage, and patient-reported outcome measures such as SRS-22, SF-36, and EQ-5D questionnaires. Data quality will be ensured through regular audits, and the total participation duration includes up to three years of follow-up.

Clinical Effectiveness of Intervertebral Disc Release in Treating Lenke 5 Adolescent Idiopathic Scoliosis