Actively Recruiting
Comparing Ringers Lactate and SterofundinPlasmalyte Fluids in Adults with Sepsis After Abdominal Surgery
Led by CMH Lahore Medical College and Institute of Dentistry · Updated on 2025-12-16
82
Participants Needed
1
Research Sites
4 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are evaluating the effects of two types of intravenous fluids, Ringers Lactate and SterofundinPlasmalyte, in adults who have had abdominal surgery and developed sepsis. The study aims to determine if there are differences in clinical outcomes between these fluids, focusing primarily on changes in serum lactate levels. Secondary outcomes include kidney function, qSOFA scores, and complications after surgery within the first 72 hours. Participants will be randomly assigned to receive either Ringers Lactate or Sterofundin as maintenance fluids through intravenous infusion. The amount and rate of fluid given will be decided by the treating doctors. This treatment will continue for 72 hours after the patient joins the study. During the study, blood samples will be collected before or immediately after surgery and at set times, such as 24 and 48 hours post-surgery, to measure serum lactate. Researchers will monitor kidney function and record any complications within 72 hours after surgery. The trial will last from November 2025 until June 2026, involving ongoing assessments during the treatment period.
CONDITIONS
Brief Title
Clinical Effects of Ringers Lactate Versus Sterofundin/ Plasmalyte Solution in Patients With Sepsis
Research Team
K
Khadija Dr. Zubair, MBBS
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