Actively Recruiting

Phase 4
Age: 18Years - 80Years
All Genders
NCT05626348

The Clinical Efficacy of Immunomodulators in RA Patients

Led by Qilu Hospital of Shandong University · Updated on 2022-11-29

400

Participants Needed

1

Research Sites

262 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study includes naive patients and csDMARDs-IR RA patients, treated with different regimens such as Iguratimod combination of different csDMARDs, or csDMARD with TNF inhibitors for 24 weeks. The disease activity and drug response will be observed. The immune disorder and synovial function will be evaluated at the same time.

CONDITIONS

Official Title

The Clinical Efficacy of Immunomodulators in RA Patients

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with rheumatoid arthritis meeting ACR 1987 or ACR/EULAR 2010 classification criteria and having knee dysfunction
  • Patients with osteoarthritis meeting 1995 classification criteria for knee osteoarthritis and having knee dysfunction
  • Age over 18 years
  • Voluntary participation with signed informed consent
  • Healthy volunteers matched by age and sex for control group
Not Eligible

You will not qualify if you...

  • Patients with active hepatitis
  • Patients with active tuberculosis
  • Patients with infection or malignancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Qilu Hospital

Jinan, Shandong, China, 250012

Actively Recruiting

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Research Team

Q

Qiang Shu, Dr.

CONTACT

B

Bingbing Ren

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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