Actively Recruiting
Clinical Efficacy and Mechanism of tDCS for Dysphagia in PD
Led by Wang Ping · Updated on 2025-09-04
58
Participants Needed
1
Research Sites
245 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to verify transcranial direct current stimulation(tDCS) efficacy for Parkinson's disease (PD)-related dysphagia and its mechanism. Subjects are randomly split into two groups: control (sham tDCS + conventional dysphagia treatment) and experimental (real tDCS + conventional treatment). Assessments will be conducted at baseline, after the completion of intervention, and at the 3-month follow-up. Swallowing function will be evaluated via gold-standard videofluoroscopic swallowing study (VFSS) and scales. Resting-state functional magnetic resonance imaging (rs-fMRI) or functional near-infrared spectroscopy (fNIRS) will be measures for tracking changes in abnormal brain regions/networks. Correlations between swallowing recovery and brain function changes, plus group imaging differences, will reveal tDCS's neurophysiological mechanism.
CONDITIONS
Official Title
Clinical Efficacy and Mechanism of tDCS for Dysphagia in PD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Meet the Chinese Diagnostic Criteria for Parkinson's Disease (2016) or MDS Diagnostic Criteria for Multiple System Atrophy or Progressive Supranuclear Palsy
- Dysphagia confirmed by videofluoroscopic swallowing study (VFSS)
- Mini-Mental State Examination (MMSE) score greater than 23
- Willing to cooperate with the study and sign informed consent
You will not qualify if you...
- Having other diseases that cause dysphagia
- Having pneumonia or severe cardiac or renal insufficiency
- Having metal implants in the body
- Cognitive impairment or inability to cooperate
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310000
Actively Recruiting
Research Team
P
Ping Wang, MS
CONTACT
B
Bo Wang, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here