Comparing Microneedling with Topical Silymarin, Diode Laser, and Scalpel for Treating Gingival Pigmentation

What this Trial Is About

Researchers are evaluating the effectiveness of the microneedling technique combined with topical silymarin application in treating gingival hyperpigmentation. This study compares this method with conventional scalpel and diode laser treatments to determine any clinical or aesthetic advantages. It also aims to identify any medical issues participants may experience when using topical silymarin. Participants will be divided into three groups one receiving scalpel de-epithelization, another treated with a diode laser device, and the third undergoing microneedling with the Dr.Pen ULTIMA - A6 needle tip, followed by topical application of silymarin for ten minutes. The laser uses a wavelength of 980 nm with a 320-micron tip, while microneedling involves repetitive punctures at various speeds and needle arrangements. During the study, researchers will monitor gingival pigmentation recurrence over six months and record post-operative pain on days 1, 3, 5, and 7 after treatment. The study includes assessments of clinical and aesthetic outcomes to evaluate the treatments. Participants will be observed for any adverse effects, especially related to silymarin use, throughout the follow-up period.

Clinical Evaluation of Microneedling Technique With Topical Application of Silymarin on Gingival Hyperpigmentation in Comparison With Diode Laser and Scalpel Methods.