Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07146165

Clinical Evaluation of a New Platform for Bi-manual Endoscopic Resection in the Rectum and Sigma (EndoTEM)

Led by Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF) · Updated on 2026-03-31

30

Participants Needed

3

Research Sites

147 weeks

Total Duration

On this page

Sponsors

R

Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF)

Lead Sponsor

O

Ovesco Endoscopy AG

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to determine whether the use of the EndoTEM system during the endoscopic removal of polyps in the distal colon is feasible and safe. The main questions it aims to answer are: * Is the use of the EndoTEM system during the endoscopic removal of polyps in the distal colon feasible (i.e., does it enable complete resection of the polyp)? * Is the use of the EndoTEM system during the endoscopic removal of polyps in the distal colon safe? Participants will: * be treated with the EndoTEM system during the endoscopic submucosal dissection of polyps in the distal colon. * answere questionnaires on fecal continence and quality of life before and after the intervention. * be treated following standard clinical procedures before, during and after the endoscopic removal.

CONDITIONS

Official Title

Clinical Evaluation of a New Platform for Bi-manual Endoscopic Resection in the Rectum and Sigma (EndoTEM)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Availability of written informed consent from the patient
  • Age > 18 years
  • Adenoma or early carcinoma > 2 cm in the rectum or distal sigmoid colon with indication for endoscopic en bloc resection using endoscopic submucosal dissection
Not Eligible

You will not qualify if you...

  • Informed consent not possible (e.g., language barrier)
  • Stenoses or fistulas in the anal region
  • Distance to the anocutaneous line ≤ 2 cm
  • Distance to the anocutaneous line > 20 cm
  • Individual medical assessment required for patients taking anticoagulant medication, in accordance with current ESGE guidelines
  • Pregnancy or breastfeeding
  • Vulnerable individuals

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Universitätsklinikum Freiburg, Klinik für Innere Medizin II

Freiburg im Breisgau, Germany, 79106

Not Yet Recruiting

2

RKH Klinikum Ludwigsburg

Ludwigsburg, Germany, 71640

Not Yet Recruiting

3

Robert Bosch Krankenhaus GmbH

Stuttgart, Germany, 70376

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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