Actively Recruiting
The Clinical Feasibility and Validity of PMIvent to Access Inspiratory Effort During Pressure Support Ventilation
Led by Jian-Xin Zhou · Updated on 2024-07-25
25
Participants Needed
1
Research Sites
96 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
It is critical to maintain a relatively normal inspiratory effort during pressure support ventilation (PSV), the support level should be adjusted to match the patient's inspiratory effort. The inspiratory muscle pressure index (PMI) can reflect the elastic work of the respiratory system at the end of inspiration and has a significant correlation with inspiratory effort, and it has the outgoing advantages of being non-invasive and easy to obtain. Previous studies on PMI were based on physiological research and experimental conditions (PMIref), which require special pressure monitoring devices and software to collect and measure airway pressure. If PMI is going to be used in clinical practice, it is necessary to find a simple measurement method of PMI to replace PMIref. Most ventilators have airway pressure monitoring and end-inspiratory holding functions, and PMI can be measured by freezing the ventilator screen (PMIvent). The overall aim of this study was to determine PMIvent's clinical feasibility and validity for accessing inspiratory effort during PSV.
CONDITIONS
Official Title
The Clinical Feasibility and Validity of PMIvent to Access Inspiratory Effort During Pressure Support Ventilation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult acute respiratory failure patients undergoing mechanical ventilation
- Enrolled 24 hours after switching to pressure support ventilation mode
You will not qualify if you...
- Age younger than 18 years or older than 85 years
- Known pregnancy or currently giving birth
- Chronic obstructive pulmonary diseases
- Gastric or esophageal injury
- Barotrauma
- Diaphragm dysfunction
- Intracranial hypertension or brain stem injury
- Decreased consciousness level (RASS less than -2)
- Anticipating withdrawal of life support or shift to palliative care
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Beijing Tiantan Hospital
Beijing, China
Actively Recruiting
Research Team
J
Jian-Xin Zhou, MD
CONTACT
R
Ran Gao, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
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