Actively Recruiting
Clinical Features Associated With Restless Legs Syndrome.
Led by University Hospital, Montpellier · Updated on 2021-09-24
2000
Participants Needed
1
Research Sites
313 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Restless legs syndrome (RLS) is a chronic neurological disorder characterized by an urge to move the legs at night when at rest. RLS can lead to a sleep deprivation, increased falling risk, daytime sleepiness, depression and decreased quality of life. Dopamine agonists, alpha-2-delta ligands and opiates are key medications for RLS. The natural course of RLS is very heterogeneous with a risk of increasing the severity of symptoms over the years despite the use of drugs and recommended dosages. Many comorbidities can make RLS worse. Augmentation syndrome is the main complication of dopamine agonists. However, only a few studies have addressed the clinical, biological and pharmacological factors associated with the evolution of the severity of RLS. The objective of this study is to assess the evolution of RLS symptoms severity as function of RLS phenotype, comorbidities and RLS medication, in large cohort of members of the French RLS association and other European RLS association.
CONDITIONS
Official Title
Clinical Features Associated With Restless Legs Syndrome.
Who Can Participate
Eligibility Criteria
You may qualify if you...
Inclusion criteria:
- Adults subjects
- Restless legs syndrome diagnosis
- Member of the restless legs syndrome association
- French speaking
- Able to understand the study
- Signed written informed consent
- Affiliated to social security
Exclusion criteria:
- Vulnerable subject : subject deprived of liberty or protected by law (trusteeship, legal guardianship)
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
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Trial Site Locations
Total: 1 location
1
Uhmontpellier
Montpellier, France, 34295
Actively Recruiting
Research Team
S
Sofiene Chenini, MD
CONTACT
Y
Yves DAUVILLIERS, MD PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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