Actively Recruiting

Phase Not Applicable
Age: 18Years +
MALE
ID06046131

Clinical, Genetic and Environmental Determinants of Prostate Cancer Progression

Led by Centre Hospitalier Universitaire de la Guadeloupe · Updated on 2025-11-17

3000

Participants Needed

2

Research Sites

N/A

Total Duration

On this page

Sponsors

C

Centre Hospitalier Universitaire de la Guadeloupe

Lead Sponsor

I

Institut National de la Santé Et de la Recherche Médicale, France

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are studying the progression and development of prostate cancer, which varies greatly between individuals based on genetic, clinical, and environmental factors as well as ethno-geographic origins. The goal is to identify factors that influence how the disease evolves, including risks of complications and treatment responses. This knowledge aims to support better treatment choices and improve prevention and screening, especially in high-risk populations. The study involves two groups of newly diagnosed prostate cancer patients from Guadeloupe and Rennes, representing different ethno-geographic backgrounds. Patients will be included before starting treatment and followed over time. Data collection includes questionnaires about lifestyle, medical and occupational history, and socio-demographic information. Biological samples like saliva, urine, and blood will be taken for genetic and environmental analysis. Patients will receive standard care, with additional sample collections for detailed biological studies. Participants will have regular follow-up visits at diagnosis and at 1, 2, 5, and 10 years after inclusion and treatment start. During these visits, clinical data, anthropometric measurements, and blood pressure will be recorded. Questionnaires will assess quality of life and other health factors. The study will measure associations between various determinants and health events related to prostate cancer progression and other health issues over time. This long-term monitoring aims to improve understanding of the disease course and outcomes.

CONDITIONS

Brief Title

Clinical, Genetic and Environmental Determinants of Prostate Cancer Progression.

Who Can Participate

Age: 18Years +
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients with a new diagnosis of prostate cancer
  • Patients consulting at the University Hospital of Guadeloupe or the University Hospital of Rennes
  • Residents of Guadeloupe, Martinique, Saint-Martin, or Brittany
  • Affiliated with or beneficiaries of social security
  • Signed informed consent
Not Eligible

You will not qualify if you...

  • Physical or mental health conditions preventing participation as judged by the investigator
  • Adults under legal protection such as guardianship, curatorship, or safeguard of justice

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Monitoring

Duration - Up to 10 years

Participants are followed over time with structured questionnaires, clinical data collection, and biological sample collection to observe disease progression and other health events.

Visits at the start of the study, and at 1, 2, 5, and 10 years after inclusion and after starting treatment

Trial Site Locations

Total: 2 locations

1

CHU of Rennes

Rennes, Ille-et-Vilaine, France, 35000

Not Yet Recruiting

2

CHU of Guadeloupe

Pointe-à-Pitre, Guadeloupe, Guadeloupe, 97159

Actively Recruiting

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Research Team

V

Valérie HAMONY-SOTER

E

Eunice NUBRET

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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