Study on How Clinical, Genetic, and Environmental Factors Affect Prostate Cancer Progression Following Diagnosis and Treatment in Different Ethnic Groups

What this Trial Is About

Researchers are studying the progression and development of prostate cancer, which varies greatly between individuals based on genetic, clinical, and environmental factors as well as ethno-geographic origins. The goal is to identify factors that influence how the disease evolves, including risks of complications and treatment responses. This knowledge aims to support better treatment choices and improve prevention and screening, especially in high-risk populations. The study involves two groups of newly diagnosed prostate cancer patients from Guadeloupe and Rennes, representing different ethno-geographic backgrounds. Patients will be included before starting treatment and followed over time. Data collection includes questionnaires about lifestyle, medical and occupational history, and socio-demographic information. Biological samples like saliva, urine, and blood will be taken for genetic and environmental analysis. Patients will receive standard care, with additional sample collections for detailed biological studies. Participants will have regular follow-up visits at diagnosis and at 1, 2, 5, and 10 years after inclusion and treatment start. During these visits, clinical data, anthropometric measurements, and blood pressure will be recorded. Questionnaires will assess quality of life and other health factors. The study will measure associations between various determinants and health events related to prostate cancer progression and other health issues over time. This long-term monitoring aims to improve understanding of the disease course and outcomes.

Clinical, Genetic and Environmental Determinants of Prostate Cancer Progression.