Study of Eldecalcitol with Whey Protein and Exercise to Treat Sarcopenia in Adults 30 and Older

What this Trial Is About

Researchers are conducting a multicenter, single-blind, randomized controlled trial to evaluate the safety and effectiveness of combined interventions for sarcopenia, a condition characterized by loss of muscle mass and strength. Participants who meet the diagnostic criteria for sarcopenia and are 30 years or older are included. The trial compares routine interventions alone and in combination with supplements to assess their impact on muscle health and physical function. Participants are divided into three groups a control group receiving routine care including nutritional guidance, progressive resistance exercise, safety advice, and treatment for complications over 24 weeks an experimental group 1 receiving the same routine care plus whey protein powder supplementation for 12 weeks at 60 grams per day in three doses and an experimental group 2 receiving routine care along with both whey protein powder and eldecalcitol capsules at 0.75 micrograms daily for 12 weeks. Liver and kidney function are monitored to adjust protein dosage if needed. Throughout the 24-week study, participants undergo regular assessments including general health evaluations, blood tests, muscle mass and strength measurements, and physical function tests like grip strength and 6-meter walking speed. Researchers also monitor adverse events to evaluate safety. The main outcome is muscle mass change, with secondary outcomes including muscle strength, walking speed, and incidence of adverse reactions.

Clinical Intervention of Idecalcitol Combined With Whey Protein Powder and Exercise for Sarcopenia