Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05835622

Clinical Investigation of the Quality of Life Benefit of Using a Home Walking Exoskeleton for a Population of Multiple Sclerosis Patients.

Led by Pôle Saint Hélier · Updated on 2025-04-09

28

Participants Needed

6

Research Sites

139 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical investigation is to evaluate the effectiveness of home use of a lightweight robotic lower limb exoskeleton as a walking aid device on quality of life in patients with multiple sclerosis with gait disorders. Participants will wear an exoskeleton (Keeogo) for 8 weeks at home during the experimental phase. This phase is compared to an 8-week control phase at home with advice on regular physical activity adapted to their abilities.

CONDITIONS

Official Title

Clinical Investigation of the Quality of Life Benefit of Using a Home Walking Exoskeleton for a Population of Multiple Sclerosis Patients.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with multiple sclerosis in the relapsing-remitting form for more than 6 months
  • Expanded Disability Status Scale (EDSS) score between 5 and 6.5
  • Living at home
  • Using a walking aid
  • 18 years old or older
  • Freely consent to participate
  • Height more than 1.52 meters
  • Hip Manual Muscle Testing score 3+ or higher (flexors and expanders)
  • Knee Manual Muscle Testing score 2 or higher (flexors and expanders)
  • Berg Balance Scale score greater than 20
  • Affiliated with or beneficiary of a social security plan
Not Eligible

You will not qualify if you...

  • Impaired comprehension preventing study completion
  • Unable to walk without assistance for 10 minutes
  • Scheduled rehabilitation stay during follow-up
  • Psychiatric conditions affecting withdrawal experience
  • Severe cognitive impairment (MMSE less than 24)
  • Person deprived of liberty by judicial or administrative decision
  • Under psychiatric care or admitted to institution not for research
  • Spasticity greater than 3 on Held and Tardieu scale in relevant muscles
  • Complete paralysis of lower limbs
  • Severe osteoporosis
  • Hip or knee replacements limiting walking or sitting
  • Severe vascular disorders of lower limbs
  • Existing wounds or skin lesions where device is worn
  • Pregnant or postpartum without lumbopelvic recovery
  • Orthopedic disorders preventing device adjustment
  • Uncontrolled epilepsy or tremors
  • Uncontrolled autonomic dysreflexia
  • Severe balance or neurological disorders preventing safe device use
  • Conditions preventing safe moderate-intensity exercise

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 6 locations

1

Hospices Civils de Lyon - Hôpital Henry Gabrielle

Saint-Genis-Laval, Auvergne-Rhône-Alpes, France, 69230

Actively Recruiting

2

Pôle Saint Hélier

Rennes, Brittany Region, France, 35000

Actively Recruiting

3

Hôpital Saint Philibert-Groupement des Hôpitaux de l'Institut Catholique de Lille

Lomme, Hauts-de-France, France, 59160

Actively Recruiting

4

Centre de rééducation Fonctionnelle Propara-Montpellier

Montpellier, Occitanie, France, 34090

Actively Recruiting

5

CHU Angers- SSR Les Capucins

Angers, Pays de la Loire Region, France, 49103

Actively Recruiting

6

CHU Nantes site de Saint Jacques

Nantes, Pays de la Loire Region, France, 44093

Actively Recruiting

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Research Team

P

Phillipe Gallien, Doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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