Actively Recruiting
Clinical Management and Outcomes of Primary Ovarian Leiomyosarcoma
Led by Azienda USL Reggio Emilia - IRCCS · Updated on 2026-05-05
30
Participants Needed
10
Research Sites
185 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This observational study aims to gather comprehensive data on primary ovarian leiomyosarcoma (POLMS). This extremely rare malignancy accounts for less than 3% of primary ovarian malignancies and has an incidence of only 1% among ovarian cancers. This national, retrospective and prospective multicenter study will collect and analyze historical cases of POLMS with remote diagnoses accessed through clinical case reviews and newly identified cases. The study aims to expand a previously identified series of 113 cases described in the literature, uncovering patterns in diagnosis, treatment, and outcomes and ultimately establishing evidence-based guidelines for the optimal management of this rare and aggressive cancer.
CONDITIONS
Official Title
Clinical Management and Outcomes of Primary Ovarian Leiomyosarcoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of primary leiomyosarcoma of the ovary
- Patients diagnosed with POLMS with available diagnostic and treatment data
- Age between 18 and 99 years
You will not qualify if you...
- Diagnosis of other ovarian sarcomas such as rhabdomyosarcomas, fibrosarcomas, or stromal cell sarcomas
- Diagnosis of leiomyosarcoma of the uterus
AI-Screening
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Trial Site Locations
Total: 10 locations
1
AOU Policlinico di Modena
Modena, Italy, Italy, 41125
Actively Recruiting
2
Azienda Ospedaliero Universitaria di Parma - S.C. Ostetricia e Ginecologia
Parma, PR, Italy, 43126
Actively Recruiting
3
Azienda USL IRCCS di Reggio Emilia
Reggio Emilia, RE, Italy, 42123
Actively Recruiting
4
Malzoni - Avellino
Avellino, Italy, 83100
Actively Recruiting
5
Azienda Ospedaliero Universitaria Policlinico "G.Rodolico - San Marco" - Catania
Catania, Italy, 95123
Actively Recruiting
6
IRCCS Ospedale San Raffaele
Milan, Italy, 20132
Actively Recruiting
7
Fondazione Irccs San Gerardo Dei Tintori
Monza, Italy
Actively Recruiting
8
IRCCS Istituto Nazionale Tumori Fondazione Pascale
Naples, Italy, 80131
Actively Recruiting
9
Università degli Studi di Napoli Federico II
Naples, Italy
Actively Recruiting
10
Ospedale "Sacro Cuore"
Verona, Italy
Actively Recruiting
Research Team
V
Vincenzo Dario Mandato, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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