Actively Recruiting
Clinical and Molecular Features of Oral Premalignancy and Oral Cancer
Led by M.D. Anderson Cancer Center · Updated on 2026-04-16
1000
Participants Needed
1
Research Sites
2200 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Investigators will employ serial assessments of tissue biopsy and additional biomarkers that reflect burden of disease and predict treatment response. Patients enrolled on this study will be given the option to provide biological samples before, during, and after treatment, as well as functional outcomes of treatment response. These samples will be utilized to develop and validate prognostic and predictive biomarkers for patients undergoing targeted therapy, immunotherapy, surgery, chemotherapy, and/or radiotherapy.
CONDITIONS
Official Title
Clinical and Molecular Features of Oral Premalignancy and Oral Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 or older, with a diagnosis of oral premalignant or malignant tumors or presenting with suspected premalignant or malignant tumors for definitive diagnosis
- Must be able to provide informed consent
- Oral premalignant or malignant tumors presenting for evaluation for the first time at UT MD Anderson Cancer Center
- Oral premalignant or malignant tumors previously treated or evaluated at UT MD Anderson Cancer Center presenting with progressive or recurrent disease
- Eligible diagnoses include leukoplakia, erythroplakia, mild/moderate/severe dysplasia, carcinoma in situ, and squamous cell carcinoma
You will not qualify if you...
- Pregnant women
- Cognitively-impaired adults
- Prior oral squamous cell carcinoma surgery or radiation treatment at a non-MDA institution
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
MD Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
X
Xiao Zhao, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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