Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT03303612

Clinical Monitoring Strategy Versus Electrophysiology-guided Algorithmic Approach With a New LBBB After TAVI

Led by Montreal Heart Institute · Updated on 2025-05-08

250

Participants Needed

10

Research Sites

476 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The primary hypothesis of the proposed study is that an electrophysiology-based algorithmic approach is superior to standard clinical follow-up with 30-day monitoring in reducing the combined endpoint of syncope, hospitalization, and death in patients in patients with new of left bundle branch block following transcatheter aortic valve implantation (TAVI).

CONDITIONS

Official Title

Clinical Monitoring Strategy Versus Electrophysiology-guided Algorithmic Approach With a New LBBB After TAVI

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Provided informed consent to participate
  • Persistent new-onset left bundle branch block after transcatheter aortic valve implantation present at day 2
Not Eligible

You will not qualify if you...

  • Previous pacemaker or implantable cardioverter-defibrillator
  • Pre-existing right bundle branch block or left bundle branch block before TAVI
  • Class I or IIA indication for permanent pacemaker implantation according to guidelines

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 10 locations

1

Mazankowski Alberta Heart Institute

Edmonton, Alberta, Canada

Actively Recruiting

2

New Brunswick Heart Center

Saint John, New Brunswick, Canada

Not Yet Recruiting

3

QEII Health Sciences Center

Halifax, Nova Scotia, Canada

Actively Recruiting

4

Hamilton Health Sciences Corporation

Hamilton, Ontario, Canada

Actively Recruiting

5

London Health Sciences Center (LHSC)

London, Ontario, Canada

Actively Recruiting

6

University of Ottawa Heart Institute (UOHI)

Ottawa, Ontario, Canada

Actively Recruiting

7

Montreal Heart Institute

Montreal, Quebec, Canada, H1T1C8

Actively Recruiting

8

CIUSSS du Nord de l'Île de Mtl

Montreal, Quebec, Canada

Actively Recruiting

9

Centre hospitalier universitaire de Sherbrooke

Sherbrooke, Quebec, Canada, Canada, J1J 3H5

Actively Recruiting

10

Centre Hospitalier Universitaire de Nantes

Nantes, Cedex 01, France

Not Yet Recruiting

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Research Team

L

Léna Rivard, MD, MSc

CONTACT

C

Caroline Girard, EP Prof.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Clinical Monitoring Strategy Versus Electrophysiology-guided Algorithmic Approach With a New LBBB After TAVI | DecenTrialz