What is this study trying to find out about left bundle branch block (LBBB)?

This study is observing patients with LBBB to understand how it affects heart function and health outcomes. Researchers want to identify features that predict when LBBB causes left ventricular dysfunction and adverse events. The goal is to gather information that may help guide future treatments.

Who may be eligible for this left bundle branch block (LBBB) clinical trial?

Adults aged 18 years or older with a diagnosis of LBBB on ECG may be eligible. The study accepts all genders but excludes those with prior major heart attacks, certain heart surgeries, congenital heart defects, or permanent pacing devices. Please review eligibility criteria for more details.

Is there any cost to participate in this left bundle branch block (LBBB) clinical trial?

Study-related care, including all diagnostic tests and clinical follow-up visits, is provided at no cost. However, personal travel and related expenses may vary and are not guaranteed to be covered. Participants should plan accordingly.

Actively Recruiting

Age: 18Years +

All Genders

ID05283603

Observational Study of Patients with Left Bundle Branch Block Using ECG and Imaging to Track Heart Function and Outcomes

Led by Azienda Ospedaliero Universitaria di Sassari · Updated on 2022-03-17

1000

Participants Needed

Research Sites

424 weeks

Total Duration

AI-Summary

What this Trial Is About

This research focuses on patients who have left bundle branch block LBBB as seen on their ECG. The study aims to explore the clinical, ECG, and imaging features in a large group of these patients. It seeks to find factors that predict when LBBB causes left ventricular systolic dysfunction and to identify outcomes for this population, with the goal of providing data that may influence treatment approaches. Participants will undergo clinical and instrumental follow-up using diagnostic tests such as ECG, echocardiogram, and magnetic resonance imaging. These assessments will help monitor heart function and detect changes over time. The study is observational, meaning it tracks patients without assigning specific treatments. Throughout the study, participants will be regularly evaluated using these tests to monitor left ventricular function and any cardiovascular events like heart failure. The main outcome measured is left ventricular dysfunction over a follow-up period of 20 years. Secondary outcomes include adverse cardiovascular events. This long-term monitoring helps researchers understand the progression and impact of LBBB on heart health.

CONDITIONS

Brief Title

Clinical Observational Registry of Patients With Left Bundle Branch Block

Who Can Participate

Age: 18Years +

All Genders

Eligibility Criteria

You may qualify if you...

LBBB on ECG
Age 18 years or older

You will not qualify if you...

Previous extensive anterior myocardial infarction
Previous cardiac surgery or transcatheter aortic valve implantation (TAVI)
Congenital structural heart disease
Patients implanted with permanent right ventricular stimulation devices and permanent pacing
Denial to consent

Research Team

Giuseppe D Sanna, MD PhD

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