Actively Recruiting
Clinical Outcomes and Pharmacotherapy Effectiveness in the VA Health Care System (COPE-VA)
Led by VA Office of Research and Development · Updated on 2026-02-10
400000
Participants Needed
1
Research Sites
261 weeks
Total Duration
On this page
Sponsors
V
VA Office of Research and Development
Lead Sponsor
B
Biomedical Advanced Research and Development Authority
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to comprehensively describe the temporal and geographic utilization of COVID-19 therapies used for mild to moderate disease during different periods of SARS-CoV-2 variant circulation as well as to compare demographic and clinical characteristics of Veterans who are treated or do not receive these different therapies. The investigators will also perform similar descriptive epidemiology for other respiratory viruses, including RSV and influenza and other infectious diseases. This first phase will critically inform feasibility and direction of the second phase, in which the investigators will use target trial emulation design to study the comparative effectiveness of therapies and vaccines for COVID-19, respiratory viruses, including RSV, and influenza, and other infectious diseases.
CONDITIONS
Official Title
Clinical Outcomes and Pharmacotherapy Effectiveness in the VA Health Care System (COPE-VA)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Veterans aged 18 years with a laboratory-confirmed positive test for SARS-CoV-2 or a diagnosis of COVID-19 documented at any time since January 2020
- All Veterans aged 18 years alive and in VHA care as of January 2018
- Specific exclusion/inclusion criteria and observation periods will be defined for each sub-study
You will not qualify if you...
- VA employees who are not enrollees
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
VA Portland Health Care System, Portland, OR
Portland, Oregon, United States, 97207-2964
Actively Recruiting
Research Team
K
Kristina L Bajema, MD
CONTACT
G
George N Ioannou, MD MS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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