Actively Recruiting
Clinical Performance of Printed Hybrid Resin in Indirect Restorations
Led by Universitat Internacional de Catalunya · Updated on 2026-03-16
60
Participants Needed
1
Research Sites
128 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This randomized clinical trial aims to evaluate the clinical performance of a 3D-printed hybrid resin (VarseoSmile TriniQ) used for indirect restorations in endodontically treated teeth, compared with a CAD/CAM composite block (Cerasmart). In addition, two different luting protocols will be compared: a preheated microhybrid composite (Enamel Plus HRi) and a resin cement (RelyX Universal). Sixty patients requiring restoration of an endodontically treated molar with an indirect adhesive overlay will be recruited at the University Dental Clinic of the Universitat Internacional de Catalunya (Barcelona, Spain). Participants will be randomly assigned to receive restorations fabricated either using the printed hybrid resin or the CAD/CAM composite material. Each material group will be further divided according to the cementation technique used. All restorations will be fabricated following a digital workflow that includes intraoral scanning, CAD design, and either additive manufacturing (3D printing) or subtractive milling. Adhesive luting procedures will be performed according to standardized clinical protocols. Clinical evaluations will be performed at baseline, 3 months, 6 months, and 12 months, and annually thereafter. The clinical performance of the restorations will be assessed using modified United States Public Health Service (USPHS) criteria, including parameters such as marginal adaptation, contact points, color stability, wear, fracture occurrence, secondary caries, and patient comfort. The results of this study will provide clinical evidence regarding the behavior of 3D-printed hybrid resin restorations and their potential use as an alternative to conventional CAD/CAM composite materials for indirect restorations in endodontically treated teeth.
CONDITIONS
Official Title
Clinical Performance of Printed Hybrid Resin in Indirect Restorations
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Signed informed consent
- Need to restore an endodontically treated molar with an indirect adhesive overlay
- Physically and psychologically able to tolerate conventional restorative procedures
- No high caries risk
- No active periodontal disease
- Natural antagonist tooth present
- Need for full cuspal coverage restoration (overlay)
- Remaining wall thickness less than 3 mm in the endodontically treated tooth
- Occlusal thickness of the restoration 1 mm or more
- Willing and able to attend follow-up visits
You will not qualify if you...
- Poor oral hygiene
- Uncontrolled parafunctional habits such as bruxism
- High caries risk
- Active periodontal disease
- Active pulpal disease
- Absence of natural antagonist tooth
- Need for partial cuspal coverage restoration such as inlay or onlay
- Insufficient space between teeth for the restoration
- Teeth planned as abutments for removable or fixed prostheses
- Known allergy to any materials used in the study
AI-Screening
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Trial Site Locations
Total: 1 location
1
Clínica Universitària d'Odontologia UIC Barcelona
Sant Cugat del Vallès, Barcelona, Spain, 08195
Actively Recruiting
Research Team
M
MARTA VALLES, DDS, PhD
CONTACT
P
Patricia Freire, DDS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
TREATMENT
Number of Arms
4
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