Actively Recruiting
Construction of a Clinical Prediction Model for In-Hospital Rebleeding in Patients With Acute Non-Venous Upper Gastrointestinal Bleeding
Led by Junwei Yan · Updated on 2024-11-27
1000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Acute Non-variceal Upper Gastrointestinal Bleeding (ANVUGIB) is a serious condition causing symptoms such as vomiting blood or passing black stools. Despite improved treatments, 10% to 30% of patients experience rebleeding soon after initial treatment, which raises the risk of death. Researchers are working to develop a new, more accurate prediction model to better identify patients at high risk of rebleeding compared to current tools like the Glasgow-Blatchford Score and Rockall Score. This model aims to help doctors make better decisions about preventive treatments and monitoring to reduce complications and improve outcomes. This observational study collects patient data during routine care to build and test this new prediction model. It will combine patient symptoms, lab test results, and imaging findings to improve risk assessment for rebleeding. Participants include adults diagnosed with ANVUGIB who receive an endoscopy within 24 hours of admission confirming non-variceal bleeding. The study focuses on evaluating rebleeding events within seven days of hospitalization. Participants will be monitored using data from their clinical care, including symptoms, lab tests, and imaging results. Researchers will measure the occurrence of rebleeding up to seven days after admission. No experimental treatments are given, and the study directly uses existing patient information to develop the prediction model. Participation involves routine procedures, and the study aims to improve future care by providing doctors with a better tool for identifying high-risk patients.
CONDITIONS
Brief Title
Clinical Prediction Model for In-Hospital Rebleeding in Acute Non-Variceal Upper Gastrointestinal Bleeding
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18 years
- Clinical diagnosis of Acute Non-Variceal Upper Gastrointestinal Bleeding
- Underwent endoscopy within 24 hours of admission confirming non-variceal bleeding
You will not qualify if you...
- Upper Gastrointestinal Bleeding during hospitalization
- Transfer from other hospitals
- Variceal bleeding
- Lower gastrointestinal bleeding
- Bleeding due to systemic diseases like disseminated intravascular coagulation and hematological disorders
- Incomplete clinical or laboratory data
- Patients who requested early discharge or declined gastroscopy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Within 1 day
Participants undergo endoscopy within 24 hours of admission to confirm non-variceal upper gastrointestinal bleeding.
1 visit (in-person)
Duration - Up to 7 days
Participants are observed for signs of in-hospital rebleeding following diagnosis.
Daily assessments during hospitalization
Trial Site Locations
Total: 1 location
1
the Central Hospital of Wuhan
Wuhan, Hubei, China, 430000
Actively Recruiting
Research Team
J
junwei yan
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Frequently Asked Questions
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