Actively Recruiting
Clinical and Radiographic Evaluation of Allogenic Dentin Grafts for Alveolar Ridge Preservation
Led by Jordan University Hospital · Updated on 2025-02-14
10
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
Sponsors
J
Jordan University Hospital
Lead Sponsor
H
hanan Jafar
Collaborating Sponsor
AI-Summary
What this Trial Is About
For the first time, allografts from human-extracted teeth will be prepared and evaluated in a prospective clinical trial to assess their efficacy for alveolar ridge preservation. The reconstruction and preservation of the alveolar ridge after tooth extraction are essential for future prosthetic rehabilitation. Autogenous bone grafts, while effective, are limited by donor site morbidity and insufficient graft quantity. Allogenic dentin grafts from healthy human donors present a scalable solution. This study aims to evaluate the biocompatibility and effectiveness of two types of allogenic dentin grafts-demineralized dentin allografts (DDA) and whole tooth allografts (WTA)-for alveolar ridge preservation, contributing to innovative, sustainable dental practices.
CONDITIONS
Official Title
Clinical and Radiographic Evaluation of Allogenic Dentin Grafts for Alveolar Ridge Preservation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 to 60 years requiring extraction of at least three teeth for clinical or therapeutic reasons
- Patients in good systemic health without conditions impairing bone healing
- Willingness to provide informed consent and participate in follow-ups
- Donors must be students, interns, or residents willing to participate and provide informed consent
- Donors must have no history of systemic diseases such as diabetes, hepatitis, or immune disorders
- Donors must have negative blood screening for HIV, HBV, and HCV
- Donors must be non-smokers or have not smoked within the last six months
You will not qualify if you...
- History of systemic conditions affecting oral or overall health
- Positive blood tests for communicable diseases
- Active oral infections or untreated dental caries
- Pregnancy or lactation
- History of smoking or substance abuse within the last six months
- Systemic conditions such as diabetes, osteoporosis, or immunodeficiency impairing bone regeneration
- History of radiation therapy to the head and neck
- Use of medications affecting bone metabolism (e.g., bisphosphonates, steroids)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Jordan University Hospital
Amman, Jordan, 00962
Actively Recruiting
Research Team
S
Soukaina Ryalat, Prof
CONTACT
H
Hanan Jafar, Dr
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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