Evaluating Human-Derived Allogenic Dentin Grafts for Alveolar Ridge Preservation After Tooth Extraction in Adults

What this Trial Is About

Researchers are evaluating the use of allogenic dentin grafts, derived from human-extracted teeth, for preserving the alveolar ridge after tooth extraction. This trial aims to test two types of grafts demineralized dentin allografts DDA and whole tooth allografts WTA, as alternatives to traditional autogenous bone grafts. These grafts may offer a sustainable and scalable solution by repurposing extracted teeth, which are usually discarded, and addressing the limitations of autogenous grafts such as donor site issues and limited availability. Participants will receive one of the two allogenic dentin grafts DDA or WTA applied to preserve the alveolar ridge following tooth extraction, or no graft in the control group. The study is prospective and non-randomized, focusing on clinical and radiographic evaluation. The grafts are prepared from healthy human donors, and the intervention supports innovative, sustainable dental practices. The trial includes a control group to compare outcomes without grafting. During the study, participants will undergo assessments including cone beam computed tomography CBCT scans to measure changes in alveolar ridge width and height from baseline to three months after extraction. Researchers will monitor the biocompatibility and effectiveness of the grafts by comparing these measurements across groups. The total follow-up period for primary outcomes is three months post-extraction, with evaluations of alveolar crest dimensions to support future prosthetic rehabilitation.

Clinical and Radiographic Evaluation of Allogenic Dentin Grafts for Alveolar Ridge Preservation