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Clinical, Radiographic, Functional and Psychosocial Evaluation of Premolar Autotransplantation to the Anterior Maxillary Region in Young Patients: An Ambispective Observational Study
Led by University of Barcelona · Updated on 2026-01-02
50
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to assess the clinical, radiographic, functional, and patient-reported outcomes of premolar autotransplantation used to replace anterior maxillary teeth in young patients aged 7 to 15 years. It combines a retrospective cohort of patients treated between December 2019 and December 2025 with a prospective cohort enrolling patients until December 2028. The goal is to identify long-term success factors and prognostic indicators for this dental procedure in growing patients. Premolar autotransplantation is performed following a standardized clinical protocol involving digital planning with CBCT and STL models, 3D-printed donor tooth replicas, guided or conventional socket preparation, atraumatic donor extraction with extraoral time under 5 minutes, and semirigid splinting. Both cohorts follow identical surgical, orthodontic, radiographic, and follow-up protocols with clinical and radiographic evaluations up to 5 years. Participants are monitored at multiple time points including 1 week, 15 days, 1, 2, 3, 6, 9, and 12 months, then annually for up to 5 years. Assessments include tooth mobility, sensitivity, percussion sound, periodontal measurements, gingival recession, root development, pulpal healing, and radiographic signs of complications. Patient satisfaction, esthetics, function, and oral health-related quality of life are also evaluated using validated questionnaires. Data is analyzed to determine tooth survival, complications, orthodontic interactions, restorative needs, and overall outcomes.
CONDITIONS
Brief Title
Clinical and Radiological Evaluation of Dental Autotransplantation in the Anterior Region in Young Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 7 to 15 years.
- ASA I classification (healthy without severe systemic disease).
- Loss or indication for extraction of a maxillary anterior tooth (teeth 12, 11, 21, or 22) due to trauma, resorption, or restorative reasons.
- Availability of a donor first or second premolar with root development between one-half and complete root length.
- Ability to complete at least 2 years of follow-up.
- Parent/guardian consent and minor assent obtained for prospective cases.
You will not qualify if you...
- Patients older than 15 years.
- Severe systemic disease.
- Inability or unwillingness to attend scheduled follow-up visits.
- Lack of a suitable donor premolar.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of transplantation
Participants undergo premolar autotransplantation following a standardized clinical protocol including digital planning, donor tooth extraction, and transplantation.
1 visit (in-person)
Duration - Up to 5 years
Participants receive clinical and radiographic follow-ups to assess healing, root development, and complications over time.
Visits at 1 week, 15 days, 1, 2, 3, 6, 9, and 12 months, then annually up to 5 years
Trial Site Locations
Total: 1 location
1
Dental Esthetic BCN
Barcelona, Barcelons, Spain, 08034
Actively Recruiting
Research Team
M
Montserrat Mercadé, PhD
J
Jordi Cadellans, DDS
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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