Clinical Retrospective Study Analysis of Postoperative Complications Following Hepatectomy

What this Trial Is About

Researchers are conducting a retrospective study to analyze complications following hepatectomy, a key surgical treatment for liver diseases like liver cancer, hepatic hemangiomas, and biliary stones. While hepatectomy has shown significant benefits, postoperative complications such as liver failure, hepatic vascular thrombosis, wound infections, and bile leakage remain serious concerns that threaten patient health and increase treatment costs. Prior studies have mostly focused on isolated complications with small patient groups, lacking a comprehensive overview. This observational study uses diagnostic criteria from the International Study Group for Liver Surgery (ISGLS) to identify liver failure occurring on or after the fifth day following surgery. The study groups patients into those who experienced post-hepatectomy liver failure (PHLF) and those who did not, as well as patients with and without liver cirrhosis. The research collects data retrospectively from patients who underwent liver resection surgery at participating centers. Participants' medical records will be reviewed to assess the incidence and risk factors of complications after hepatectomy. The primary outcome is the occurrence of liver failure after surgery, with mortality evaluated within 30 days post-operation. The study aims to provide clinical doctors with better guidance on preventing and managing postoperative complications by analyzing a large patient sample. The study includes adults aged 18 to 80 years who had liver surgery and excludes patients with prior cancer treatments, repeat surgeries, other malignancies, severe concurrent diseases, or incomplete data.

Clinical Retrospective Study Analysis of Postoperative Complications Following Hepatectomy