Actively Recruiting
Clinical Specialty Queue For Gestational Trophoblastic Neoplasia
Led by Women's Hospital School Of Medicine Zhejiang University · Updated on 2024-11-12
1000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
W
Women's Hospital School Of Medicine Zhejiang University
Lead Sponsor
T
Tongji Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are establishing a bidirectional cohort study focused on Gestational Trophoblastic Neoplasia (GTN), including both past cases and new patient groups. This study aims to create a unified clinical collaboration system across multiple tertiary hospitals to standardize diagnosis, treatment, and follow-up for GTN patients. The goal is to build a comprehensive clinical database, identify factors linked to chemotherapy resistance, and develop precise evaluation models to improve initial treatment outcomes. The study collects detailed baseline information from GTN patients, such as age, reproductive history, environmental and social factors, genetic data, physical exams, imaging, and pathology results. Biological samples like blood and tissue will also be gathered. During diagnosis and treatment, data on treatment plans, human chorionic gonadotropin (hCG) levels, and any toxic side effects will be recorded. After treatment, patients will be followed closely with monthly hCG level checks in the first year and then every three months for up to five years, alongside imaging and fertility assessments. Participants will provide ongoing information about their disease status, treatment responses, and long-term outcomes, including recurrence and metastasis. This data will be used to track prognosis and develop a standardized follow-up system for GTN. The primary outcome measure focuses on collecting detailed clinical and pathological features with a structured follow-up schedule to support evidence-based improvements in GTN care. The study is observational and led by the Women's Hospital School of Medicine Zhejiang University.
CONDITIONS
Brief Title
Clinical Specialty Queue For Gestational Trophoblastic Neoplasia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Clinically diagnosed with Gestational Trophoblastic Neoplasia, including invasive cases such as molar pregnancy, choriocarcinoma, PSTT, and ETT
- Able to provide complete informed consent for enrollment
You will not qualify if you...
- Having mental illness or cognitive impairment that prevents cooperation with the study
- Having concurrent malignant tumors
- Severe missing follow-up data that would affect study participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 5 years
Participants diagnosed with Gestational Trophoblastic Neoplasia are closely followed up to collect disease-related clinical and pathological features.
Monthly visits during the first year, then follow-up visits every 3 months annually for 4 years
Trial Site Locations
Total: 1 location
1
Weiguo Lv
Zhengjiang, Hangzhou, China, 310006
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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