Study of Continuous Positive Airway Pressure CPAP Effects on Atrial Fibrillation Returning After Catheter Ablation in Patients with Atrial Fibrillation and Moderate to Severe Obstructive Sleep Apnea

What this Trial Is About

Atrial fibrillation AF is a common heart rhythm problem that greatly raises the risk of serious health issues like stroke, heart failure, and dementia, affecting quality of life. This research focuses on patients with AF who also have moderate to severe obstructive sleep apnea OSA, a condition that can lower the success of catheter ablation, a treatment for AF. The study aims to clarify whether using continuous positive airway pressure CPAP therapy can reduce the chance of AF returning after ablation, as previous studies have shown mixed results and further real-world data is needed. Participants are divided into two groups one receives catheter ablation combined with CPAP therapy for OSA, while the other receives catheter ablation and conventional treatment without CPAP. All patients undergo overnight testing to determine the appropriate CPAP pressure, and those in the CPAP group are asked to use the device at home for at least five days a week, with a minimum of four hours per session. The study monitors participants for up to 12 months after ablation to compare outcomes between these two groups. During the study, researchers track the recurrence and burden of AF at 3, 6, 9, and 12 months after ablation. They also assess the impact of combining antiarrhythmic drugs with treatment. Quality of life is measured using surveys at 3 and 12 months. The study includes regular follow-up visits and evaluations to monitor heart rhythm, treatment adherence, and overall health, aiming to provide guidance on managing AF in patients with OSA.

Clinical Study on the Effect of CPAP on AF Recurrence After Catheter Ablation in Patients with AF and OSA