Actively Recruiting
Clinical Study on the Effectiveness of Diverse Segments Defocus Optimization in Spectacle Lenses for Slowing Myopia Progression
Led by Beijing Tongren Hospital · Updated on 2026-01-07
120
Participants Needed
1
Research Sites
112 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Clinical Trial The goal of this clinical trial is to evaluate the effectiveness of two types of Diverse Segments Defocus Optimization (D.S.D.O.) spectacle lenses in slowing myopia progression in children. It will also assess the safety of these lenses. The main questions it aims to answer are: Do D.S.D.O. lenses reduce the progression of myopia as measured by changes in cycloplegic refraction and axial length? What adverse events do participants experience when wearing D.S.D.O. lenses? Researchers will compare two optical designs of D.S.D.O. lenses (Intervention Group1: Design 1; Intervention Group2: Design 2) to determine their relative efficacy in controlling myopia progression. Participants will: Wear assigned D.S.D.O. lenses daily for 12 months (except during sleep or unavoidable situations). Attend clinic visits at baseline, 3, 6, 9, and 12 months for comprehensive eye examinations. Maintain a diary recording daily wear time, visual symptoms, and any adverse events.
CONDITIONS
Official Title
Clinical Study on the Effectiveness of Diverse Segments Defocus Optimization in Spectacle Lenses for Slowing Myopia Progression
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 6 to 14 years
- Myopic spherical equivalent refraction between -0.75D and -4.00D based on cycloplegic refraction
- Astigmatism of 1.50D or less
- Anisometropia of 1.50D or less
- Best-corrected visual acuity of 5.0 (0.00 LogMAR) or better in both eyes
- Monocular best-corrected visual acuity of 5.0 (0.00 LogMAR) or better after wearing myopic defocus spectacles
- No organic ocular diseases
- No history of myopia control treatment within the past three months
- Voluntary participation with signed informed consent
You will not qualify if you...
- History of ocular trauma or surgery
- Systemic diseases affecting visual function
- Inability to cooperate with examinations
- Poor compliance
- Inability to follow wearing requirements and attend follow-up visits during the trial
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Beijing Tongren Hospital
Beijing, China
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here