Actively Recruiting

Phase 2
Phase 3
Age: 18Years +
All Genders
NCT06554509

Clinical Study of the Efficacy and Safety of SHR-1819 Injection in Adult Patients With Prurigo Nodularis

Led by Guangdong Hengrui Pharmaceutical Co., Ltd · Updated on 2026-04-29

423

Participants Needed

1

Research Sites

210 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This trial was designed to evaluate the efficacy and safety of SHR-1819 injection in patients with Prurigo Nodularis.

CONDITIONS

Official Title

Clinical Study of the Efficacy and Safety of SHR-1819 Injection in Adult Patients With Prurigo Nodularis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Volunteers must sign informed consent and be able to communicate and complete the study as required
  • Age 18 years or older with no gender restrictions
  • Must have Prurigo Nodularis at screening
Not Eligible

You will not qualify if you...

  • Pregnant or lactating women
  • History of heavy alcohol consumption or substance abuse within 6 months before screening
  • Active skin disease or complications from other diseases affecting Prurigo Nodularis evaluation
  • Prurigo Nodularis caused by neurological or psychiatric disorders
  • Diagnosis of moderate to severe atopic dermatitis before or during screening
  • Significant diseases affecting safety or study results as judged by the investigator
  • Prior treatment with IL-4Rα targeting biologics or inadequate response/intolerance to such treatments
  • History of malignancy except certain fully treated skin or cervical cancers
  • Planned major surgeries during the study
  • Other conditions deemed unsuitable by the investigator for study participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peking University People's Hospital

Beijing, Beijing Municipality, China, 100032

Actively Recruiting

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Research Team

H

Huiliu Wang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Clinical Study of the Efficacy and Safety of SHR-1819 Injection in Adult Patients With Prurigo Nodularis | DecenTrialz