Actively Recruiting

Phase 2
Age: 18Years - 85Years
All Genders
NCT07021963

A Clinical Study to Evaluate the Long-term Safety of HRS-1893 in Hypertrophic Cardiomyopathy

Led by Shandong Suncadia Medicine Co., Ltd. · Updated on 2025-09-10

300

Participants Needed

1

Research Sites

125 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study mainly evaluates the long-term safety of HRS-1893 in subjects with hypertrophic cardiomyopathy.

CONDITIONS

Official Title

A Clinical Study to Evaluate the Long-term Safety of HRS-1893 in Hypertrophic Cardiomyopathy

Who Can Participate

Age: 18Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 85 years with hypertrophic cardiomyopathy who have previously completed HRS-1893 studies
  • Female participants of childbearing potential must have a negative serum pregnancy test within 7 days before the first dose and must not be breastfeeding during the study
  • Female participants of childbearing potential and male participants with partners of childbearing potential must agree to avoid donating sperm or eggs from consent until 3 months after the last dose and follow contraceptive guidelines
  • Ability to understand study procedures and voluntarily sign informed consent
Not Eligible

You will not qualify if you...

  • History of coronary artery disease with one or more arteries narrowed by more than 70% or history of heart attack
  • Use of negative inotropic medications other than disopyramide, beta-blockers, verapamil, or diltiazem within 4 weeks before screening
  • History of fainting or sustained ventricular tachycardia within 6 months before screening
  • Any physical or psychological condition that the investigator judges unsuitable for participation, including increased risk, poor compliance, or inability to complete the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College

Beijing, Beijing Municipality, China, 100037

Actively Recruiting

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Research Team

J

Jianhong Lv

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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