Actively Recruiting
Clinical Study to Evaluate the Possible Efficacy and Safety of Diosmin and Hesperidin Combined Therapy in Patients With Helicobacter Pylori Infection
Led by Sadat City University · Updated on 2024-08-12
46
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study intends to assess the possible effectiveness and safety of Diosmin and Hesperidin combination in patients with Helicobacter pylori Infection through evaluating its effect on stool antigen test and serum levels of inflammatory biomarkers as(TNF-A and MDA).
CONDITIONS
Official Title
Clinical Study to Evaluate the Possible Efficacy and Safety of Diosmin and Hesperidin Combined Therapy in Patients With Helicobacter Pylori Infection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Confirmed Helicobacter pylori infection through stool antigen test
- No prior eradication therapy for Helicobacter pylori
- Male or female
- Age between 18 and 75 years old
- Good mental well-being to understand the study's objectives and procedures
You will not qualify if you...
- Under 18 years of age
- Previous Helicobacter pylori eradication therapy
- Allergy or hypersensitivity to the study medications
- Use of proton pump inhibitors, H2-blockers, or antibiotics affecting H. pylori in the last month
- Use of Diosmin and/or Hesperidin in the last month
- History of gastric tumor or gastrointestinal surgery
- Severe cardiovascular, pulmonary, renal, hepatic disorders, or active malignancy
- Pregnancy or breastfeeding
- History of drug misuse or recent alcohol consumption
- Gall bladder disorders
- Use of blood thinning agents, anticonvulsants, muscle relaxants, or NSAIDs that may interact with Diosmin
- Use of anti-inflammatory or antioxidant drugs
- Inflammatory conditions such as ulcerative colitis or rheumatoid arthritis
- Conditions associated with oxidative stress such as smoking or COPD
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
National Liver Institute
Shibīn al Kawm, Egypt
Actively Recruiting
Research Team
A
Aya Mosaad Swidan
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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