Actively Recruiting

Early Phase 1
Age: 18Years - 45Years
All Genders
NCT06267183

A Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of SV001 in Chinese Healthy Adult Volunteers.

Led by Shanghai Synvida Biotechnology Co.,Ltd. · Updated on 2026-03-11

53

Participants Needed

1

Research Sites

154 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to evaluate safety, tolerability, PK and immunogenicity of SV001 compare to placebo in Chinese healthy adult volunteers.

CONDITIONS

Official Title

A Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of SV001 in Chinese Healthy Adult Volunteers.

Who Can Participate

Age: 18Years - 45Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Subjects must fully understand the trial and voluntarily sign informed consent.
  • Body Mass Index must be between 19 and 26 kg/m2.
  • Males must weigh at least 50 kg; females must weigh at least 45 kg.
  • Subjects must be in good health as judged by the investigator.
  • Reliable contraception must be used during and after the trial.
Not Eligible

You will not qualify if you...

  • History of drug or substance anaphylaxis.
  • Presence of respiratory symptoms or abnormal respiratory tract.
  • Current oral diseases that may affect drug or device use.
  • Other diseases or abnormal clinical signs.
  • History of drug abuse or positive urine narcotics test.
  • Smoking more than 5 cigarettes per day before screening.
  • Consuming over 14 alcohol units per week before screening or positive breath alcohol test.
  • Recent severe disease or major surgery before receiving the drug.
  • Use of other drugs recently before receiving the drug.
  • FEV1 or FVC less than or equal to 80% predicted value.
  • Positive for HIV, Hepatitis B, Hepatitis C, or Syphilis antibodies.
  • Difficulty with blood collection or history of blood phobia.
  • Pregnancy or lactation during screening.
  • Participation in other drug trials or drug use recently.
  • Blood donation or loss over 400 mL recently.
  • Any other condition deemed inappropriate by the investigator.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Shanghai Xuhui District Central Hospital

Shanghai, China

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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