Actively Recruiting
A Clinical Study of Evaluating Myocardial Viability in Ischemic Heart Disease with Integrated 18F-FDG PET/MR
Led by Shanghai East Hospital · Updated on 2024-12-02
100
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main purpose is to evaluate the accuracy of myocardial imaging obtained through integrated 18F-FDG PET/MR in detecting viable myocardium. The secondary objective is to evaluate whether myocardial imaging obtained through integrated 18F-FDG PET/MR can replace 18F-FDG PET combined with 99mTc MIBI SPECT/CT gated myocardial perfusion imaging.
CONDITIONS
Official Title
A Clinical Study of Evaluating Myocardial Viability in Ischemic Heart Disease with Integrated 18F-FDG PET/MR
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults under the age of 80
- Coronary angiography showing coronary artery disease with at least 2 arteries having stenosis greater than 80%
- Left ventricular ejection fraction (LVEF) less than 40%
- At least 3 months since acute myocardial infarction onset
- Patients with old myocardial infarction with no acute coronary events in past 3 months
- Patients scheduled for coronary artery bypass grafting (CABG) or combined treatment with human umbilical cord mesenchymal stem cells (iPSC)
- Agree to participate and sign informed consent
- Good compliance
You will not qualify if you...
- Patients with diabetes or poor blood glucose control (fasting blood glucose over 10mmol/L on test day)
- Allergy to MRI contrast agent
- Presence of electronic implants such as pacemakers, nerve stimulators, insulin pumps, or cochlear implants
- History of aneurysm surgery with intracranial aneurysm clips
- History of heart surgery with artificial heart valve
- Metal foreign objects in the eyes
- Metal implants or prostheses, or metal foreign bodies elsewhere in the body
- Severe liver or kidney dysfunction
- Arrhythmias including atrial fibrillation, cerebrovascular disease, or severe pulmonary heart disease
- Pregnant, planning pregnancy within 3 months, or breastfeeding
- Critically ill patients requiring life support systems
- Claustrophobia
- Other conditions deemed inappropriate by clinical trial personnel
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shanghai East Hospital
Shanghai, Shanghai Municipality, China, 200120
Actively Recruiting
Research Team
J
Jun Zhao, Professor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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