Actively Recruiting

Phase 1
Age: 18Years - 75Years
All Genders
NCT07446816

A Clinical Study Evaluating the Preliminary Anti-tumor Efficacy and Safety of Hemay181

Led by Ganzhou Hemay Pharmaceutical Co., Ltd · Updated on 2026-03-03

24

Participants Needed

1

Research Sites

86 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

An open-label phase I clinical study,which enrolled subjects with advanced solid tumors who have failed to respond to adequate standard therapies or have no available effective standard therapy.

CONDITIONS

Official Title

A Clinical Study Evaluating the Preliminary Anti-tumor Efficacy and Safety of Hemay181

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Subjects who voluntarily signed a written informed consent form before the start of the study
  • Subjects with pathologically confirmed advanced solid tumors who have failed standard therapies or have no effective standard therapy
  • Subjects with at least one measurable lesion evaluable by CT/MRI according to RECIST V1.1
  • At least 4 weeks or 5 half-lives since last treatment with recovery to Grade 1 or less adverse reactions (except alopecia any grade, hyperpigmentation any grade, or peripheral sensory neuropathy Grade 2 or less)
  • ECOG performance status of 0-1
  • Expected survival longer than 3 months
  • Women of childbearing potential and their partners not planning pregnancy and using effective contraception from consent until 6 months after last dose
Not Eligible

You will not qualify if you...

  • Women who are pregnant or breastfeeding
  • Positive tests for HIV, syphilis, hepatitis B with high HBV-DNA, or hepatitis C with high HCV-RNA
  • Received drug treatment from another clinical trial within 4 weeks before enrollment
  • Allergy to Hemay181 or its ingredients
  • History of alcohol or drug abuse, dependence, or severe mental illness
  • Any clinical or laboratory abnormalities making participation unsuitable as judged by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Xinxiang Medical University First Affiliated Hospital

Xinxiang, Henan, China, 45310

Actively Recruiting

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Research Team

X

Xu, Doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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