Actively Recruiting

Early Phase 1
Age: 2Years - 80Years
All Genders
NCT05911503

Clinical Study of High Concentration Ganciclovir Eye Drops in the Treatment of Cytomegalovirus Retinitis

Led by Tianjin Medical University · Updated on 2023-06-23

15

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Clinical study of high concentration ganciclovir eye drops in the treatment of cytomegalovirus retinitis

CONDITIONS

Official Title

Clinical Study of High Concentration Ganciclovir Eye Drops in the Treatment of Cytomegalovirus Retinitis

Who Can Participate

Age: 2Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients voluntarily participate in studies and sign informed consent forms
  • Ages 2 to 80 years, male or female
  • Patients with cytomegalovirus retinitis after hematopoietic stem cell transplantation or cord blood transplantation, with white blood cell count less than 4 x 10^9/L and platelet count between 25 x 10^9/L and less than 100 x 10^9/L, unable to use systemic medication or intravitreal injection due to infection and bleeding risks
  • Patients with cytomegalovirus retinitis with AIDS, CD4+ T cell count less than 100/µl, with high infection risk from intravitreal injection and unable to control severe CMV retinitis with systemic medication
Not Eligible

You will not qualify if you...

  • Presence of refractive interstitial opacification affecting fundus observation
  • Intravitreal ganciclovir or sodium phosphonate injections within 1 week prior to baseline
  • Other eye diseases affecting visual function such as syphilis-related eye diseases, acute retinal necrosis, congenital glaucoma, congenital corneal lesions, congenital macular degeneration
  • Severe neutropenia (less than 0.5 x 10^9) or severe thrombocytopenia (less than 25 x 10^9/L)
  • Other conditions judged by investigators as unsuitable for enrollment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Tianjin Medical University Eye Hospital

Tianjin, Tianjin Municipality, China, 300000

Actively Recruiting

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Research Team

X

xiaomin Zhang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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