Completed

Phase 3
Age: 30Years - 74Years
All Genders
ID00000565

Led by National Heart, Lung, and Blood Institute (NHLBI) · Updated on 2016-04-14

N/A

Participants Needed

N/A

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

To evaluate the efficacy of long-term intermittent positive pressure breathing (IPPB) treatment when used as an adjunct to the overall care of ambulatory outpatients with chronic obstructive pulmonary disease. The evaluation compared the use of IPPB with use of a powered nebulizer.

CONDITIONS

Official Title

Clinical Study of Intermittent Positive Pressure Breathing (IPPB)

Who Can Participate

Age: 30Years - 74Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

Men and women, ages 30 to 74, who were ambulatory and had symptomatic chronic bronchitis or emphysema.

Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

Trial Site Locations

Site Locations not provided

Location information for this trial is currently unavailable.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

N/A

Allocation

RANDOMIZED

Model

N/A

Primary Purpose

TREATMENT

Number of Arms

0

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Published Research Related To This Trial

The National Institutes of Health Intermittent Positive-Pressure Breathing trial: pathology studies. I. Interrelationship between morphologic lesions.

A Nagai, W W West, J L Paul...

https://pubmed.ncbi.nlm.nih.gov/3904548

The National Institutes of Health Intermittent Positive-Pressure Breathing trial: pathology studies. II. Correlation between morphologic findings, clinical findings, and evidence of expiratory air-flow obstruction.

A Nagai, W W West, W M Thurlbeck

https://pubmed.ncbi.nlm.nih.gov/3904549

The National Institutes of Health Intermittent Positive Pressure Breathing trial--pathology studies. III. The diagnosis of emphysema.

W W West, A Nagai, J E Hodgkin...

https://pubmed.ncbi.nlm.nih.gov/3541712

Body weight in chronic obstructive pulmonary disease. The National Institutes of Health Intermittent Positive-Pressure Breathing Trial.

D O Wilson, R M Rogers, E C Wright...

https://pubmed.ncbi.nlm.nih.gov/2658702

The National Institutes of Health Intermittent Positive-Pressure Breathing Trial: pathology studies. IV. The Destructive index.

K Matsuba, T Ikeda, A Nagai...

https://pubmed.ncbi.nlm.nih.gov/2658703