Actively Recruiting
Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel Dentifrice
Led by HALEON · Updated on 2026-02-05
850
Participants Needed
3
Research Sites
45 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this clinical study is to demonstrate the superior antihypersensitivity efficacy of a novel stannous fluoride (SnF2) and potassium nitrate (KNO3) dentifrice (Investigational Product), compared to SnF2 only, KNO3 only and Vehicle dentifrices, after 8 weeks twice daily use.
CONDITIONS
Official Title
Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel Dentifrice
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed and dated informed consent (and assent if appropriate)
- Biologically male or female
- Age between 12 and 65 years inclusive at consent
- Good general, oral and mental health with no significant abnormalities affecting safety or study outcomes
- History of tooth sensitivity lasting more than six months but not more than 10 years (self-reported)
- At least 2 non-adjacent teeth with exposed dentin from erosion, abrasion, or gum recession and confirmed sensitivity to tactile and air stimuli at screening and baseline
You will not qualify if you...
- Pregnant or intending to become pregnant during the study
- Breastfeeding
- Known or suspected allergy or sensitivity to study products or their ingredients
- Participation in other investigational studies within 30 days before screening or during this study
- Participation in a tooth sensitivity study within 8 weeks before screening
- Current use or recent use (within 8 weeks) of oral care products for sensitive teeth or antihypersensitivity treatments
- Daily medications that may affect perception of tooth sensitivity
- Professional tooth desensitizing treatment within 8 weeks before screening
- Tooth bleaching procedure within 8 weeks before screening
- Dental cleaning (prophylaxis) within 4 weeks before screening
- Evidence of severe oral neglect or need for extensive dental treatment
- Active dental caries or treatment for decay within 12 months before screening
- High risk of dental caries as judged by investigator
- Specific exclusions related to test teeth
- Antibiotic use within 2 weeks before screening or baseline
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
All Sum Research Limited
Melbourne, Florida, United States, 32935
Actively Recruiting
2
Salus Research, Inc.
Fort Wayne, Indiana, United States, 46825
Actively Recruiting
3
Silverstone Research
Las Vegas, Nevada, United States, 89146
Actively Recruiting
Research Team
H
Haleon Response Center
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here