Actively Recruiting

Phase Not Applicable
Age: 45Years +
All Genders
ID07347041

Clinical Study of Myofascial Trigger Points Injection Compared to Joint Cavity Injection for Treating Hip Osteoarthritis

Led by Beijing Tiantan Hospital · Updated on 2026-01-16

1036

Participants Needed

1

Research Sites

26 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating treatments for chronic musculoskeletal pain, focusing on hip osteoarthritis, which is common and significantly affects quality of life, especially in older adults. This study compares two types of glucocorticoid injections: one at myofascial trigger points and another directly into the joint cavity. The goal is to see if the easier trigger point injection is as effective as the joint injection over the long term. Participants are randomly assigned to receive either a joint cavity injection or a myofascial trigger points injection, both using triamcinolone acetonide combined with lidocaine. The joint injection is given via an anterolateral approach with a specific mixture of lidocaine and corticosteroid, while the trigger point injection involves injecting each tender point with a small volume of solution using a fine needle. Treatments are followed by regular assessments. Participants will be monitored and evaluated at 2, 4, 8, 12, and 24 weeks after treatment, with follow-up lasting up to 2 years. Researchers will record pain scores using the Numeric Rating Scale (NRS), assess joint function with WOMAC scores, gather patient impressions of change with the PGIC scale, and track any adverse reactions. This detailed follow-up aims to determine the long-term safety and effectiveness of both injection methods.

CONDITIONS

Brief Title

Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Hip Osteoarthritis(OA)

Who Can Participate

Age: 45Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of hip osteoarthritis confirmed by at least two doctors with radiographic evidence
  • Physical exam confirming at least one myofascial trigger point
  • Disease duration longer than 3 months
  • Age 45 years or older
  • NRS pain score of 3 or higher despite prior conservative treatment
  • Signed informed consent form
Not Eligible

You will not qualify if you...

  • Allergy to corticosteroids or trial medications
  • Alcohol abuse or long-term opioid use exceeding 2 weeks or over 3 days per week for more than 1 month
  • Use of sedative or analgesic medications or long-term steroid therapy
  • Severe neurological disorders, liver or kidney dysfunction, heart failure, coagulation problems, gastric ulcers, diabetes, or inflammatory rheumatic diseases
  • Intra-articular injection within past 6 months or planned joint replacement surgery
  • Unable to use pain assessment scales
  • Presence of local or systemic infection
  • Pregnant or breastfeeding women

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Single injection visit

Participants receive either a myofascial trigger points (MTrPs) injection or a joint cavity injection with triamcinolone acetonide to treat hip osteoarthritis.

1 visit (in-person)

Follow-up

Duration - Up to 24 weeks with safety monitoring up to 1 year

Participants are monitored for pain scores, joint function, patient impressions of change, and adverse reactions following the injection treatment.

Visits at weeks 2, 4, 8, 12, and 24; additional safety monitoring visits through study completion

Trial Site Locations

Total: 1 location

1

Beijing Tiantan Hospital

Beijing, Beijing Municipality, China, 100070

Actively Recruiting

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Research Team

F

Fang Luo

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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