Actively Recruiting

Phase Not Applicable
Age: 45Years +
All Genders
NCT07347041

Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Hip Osteoarthritis(OA)

Led by Beijing Tiantan Hospital · Updated on 2026-01-16

1036

Participants Needed

1

Research Sites

78 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Chronic musculoskeletal pain (CMP) is a common disease in China, with a high incidence among the elderly, and has a significant impact on patients' quality of life. Hip osteoarthritis is a common type of CMP. Currently, both domestic and international studies have confirmed that glucocorticoid injection at myofascial trigger points(MTrPs) can alleviate patients' pain symptoms. MTrPs injection is safe and easy to operate, and can improve the clinical management efficiency of patients with knee osteoarthritis. Therefore, we designed a prospective, randomized controlled, blinded outcome, non-inferiority study to compare the long-term clinical efficacy of glucocorticoid injection at myofascial trigger points and complex intra-articular injection in treating hip osteoarthritis. Patients will be randomly divided into two groups and receive either glucocorticoid injection at MTrPs or joint cavities. After treatment, patients will be followed up for 2 years. Their NRS scores, WOMAC scores, Patient Global Impression of Change(PGIC) scale, and adverse reactions will be recorded at 2 weeks, 4 weeks, 8 weeks, 12 weeks, and 24 weeks. If the results indicate that the clinical efficacy of myofascial trigger point injection for knee osteoarthritis is not inferior to that of injection at intra-articular injection, it will provide a safe and simple treatment option that is easy to promote for patients who do not respond to conservative treatment.

CONDITIONS

Official Title

Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Hip Osteoarthritis(OA)

Who Can Participate

Age: 45Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of hip osteoarthritis with radiographic evidence (Kellgren-Lawrence grade 1-4) confirmed by at least two specialists and physical exam showing at least one myofascial trigger point
  • Disease lasting more than 3 months
  • Age 45 years or older
  • Pain score of 3 or higher on Numerical Rating Scale despite previous conservative treatment
  • Signed informed consent form
Not Eligible

You will not qualify if you...

  • Allergy to corticosteroids or trial medications
  • Alcohol abuse or long-term opioid use exceeding specified limits
  • Use of sedatives or analgesics suspected; long-term steroid therapy
  • Severe neurological disorders, serious liver or kidney problems, heart failure, blood clotting issues, gastric ulcers, diabetes, or inflammatory rheumatic diseases
  • Received intra-articular injection within past 6 months or planned joint replacement surgery
  • Unable to use pain assessment scales
  • Presence of local or systemic infection
  • Pregnant or breastfeeding

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Beijing Tiantan Hospital

Beijing, Beijing Municipality, China, 100070

Actively Recruiting

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Research Team

F

Fang Luo

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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