Actively Recruiting
A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)
Led by Merck Sharp & Dohme LLC · Updated on 2026-04-17
210
Participants Needed
14
Research Sites
175 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are looking for new vaccines to prevent pneumococcal disease, which is any infection in the lungs or other parts of the body that is caused by a type of bacteria called Streptococcus pneumoniae. V118C is a new vaccine designed to help prevent disease from Streptococcus pneumoniae bacteria. This study will look at V118C in toddlers and infants. The goal of the study is to learn how safe V118C is for children and how well they tolerate it.
CONDITIONS
Official Title
A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Stage 1: Child previously received 3 routine infant doses of Pneumococcal 20-valent conjugate vaccine (PCV20)
- Stage 1: Child is 12 through 15 months of age
- Stage 2: Child is approximately 2 months of age
- Child was born at full term (gestational age 37 weeks or more)
You will not qualify if you...
- Stage 1: Child has received a PCV dose at 10 months of age or older
- Stage 2: Child has received any pneumococcal vaccine before
- Child has a history of invasive pneumococcal disease (IPD)
- Child has known allergy to any component of V118C or PCV20 including diphtheria toxoid
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 14 locations
1
Madera Family Medical Group ( Site 1004)
Madera, California, United States, 93637
Actively Recruiting
2
Acevedo Clinical Research Associates ( Site 1029)
Miami, Florida, United States, 33142
Actively Recruiting
3
University of South Florida-Department of Pediatrics ( Site 1002)
Tampa, Florida, United States, 33606
Actively Recruiting
4
Cotton O'Neil Research Center ( Site 1039)
Topeka, Kansas, United States, 66604
Actively Recruiting
5
University of Louisville, Norton Children's Research Institute ( Site 1005)
Louisville, Kentucky, United States, 40202
Actively Recruiting
6
The Pediatric Center ( Site 1025)
Columbia, Maryland, United States, 21045
Actively Recruiting
7
Saint Louis University Center for Vaccine Development ( Site 1031)
St Louis, Missouri, United States, 63104
Actively Recruiting
8
Child Health Care Associates ( Site 1035)
East Syracuse, New York, United States, 13057
Actively Recruiting
9
Tribe Clinical Research, LLC-Pediatrics ( Site 1008)
Greenville, South Carolina, United States, 29607
Actively Recruiting
10
Tribe Clinical Research - Spartanburg ( Site 1001)
Spartanburg, South Carolina, United States, 29301
Actively Recruiting
11
Epic Medical Research - Carrollton ( Site 1038)
Carrollton, Texas, United States, 75006
Actively Recruiting
12
Epic Medical Research- Garland ( Site 1017)
Garland, Texas, United States, 75043
Actively Recruiting
13
University of Texas Medical Branch ( Site 1020)
League City, Texas, United States, 77573
Actively Recruiting
14
Pediatric Research of Charlottesville, LLC ( Site 1012)
Charlottesville, Virginia, United States, 22902
Actively Recruiting
Research Team
T
Toll Free Number
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
4
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