Actively Recruiting
Clinical Study on a Novel Strategy of Individualized Non-Invasive Neuromodulation for the Treatment of Tic Disorders in Children
Led by Shanghai Children's Medical Center · Updated on 2026-01-20
60
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to establish a novel personalized closed-loop NiBS/TMS therapeutic strategy and clinical protocol for children with Tic Disorders (TDs) through a series of scientific investigations. Additionally, it seeks to elucidate the underlying neural circuit mechanisms, enhance the therapeutic efficacy of TMS in pediatric TDs, and achieve precision neuromodulation for children with TDs.
CONDITIONS
Official Title
Clinical Study on a Novel Strategy of Individualized Non-Invasive Neuromodulation for the Treatment of Tic Disorders in Children
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children and adolescents aged 5 to 18 years
- Diagnosed with Tic Disorders according to DSM-5 criteria with normal EEG
- No prior treatment received for Tic Disorders
- Full-scale intelligence quotient (FIQ) of 70 or higher on the Wechsler Intelligence Scale for Children-Revised
You will not qualify if you...
- Full-scale intelligence quotient (FIQ) below 70 on WISC-R
- Presence of metal implants in the body
- Non-right-handedness
- Head movement greater than 2mm during fMRI scanning
- Any other neurological or psychiatric conditions such as autism spectrum disorder, epilepsy, obsessive-compulsive disorder
- Previous head trauma, neurological diseases, or major systemic illnesses
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shanghai Children's Medical Center，School of Medicine, Shanghai Jiao Tong University
Shanghai, Shanghai Municipality, China, 200127
Actively Recruiting
Research Team
J
Jun Ma, M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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