Actively Recruiting
Study Comparing Radical Right Hemicolectomy Alone Versus Radical Right Hemicolectomy with Indocyanine Green Fluorescence Imaging for Treating Right Colon Cancer
Led by Sun Yat-sen University · Updated on 2025-01-17
1200
Participants Needed
1
Research Sites
359 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the clinical outcomes of using indocyanine green fluorescence imaging during laparoscopic radical right hemicolectomy for treating right colon cancer (stages T1 to T4a, with lymph node involvement but no distant metastasis). The study compares this combined procedure to standard radical right hemicolectomy to see if adding the fluorescence imaging improves treatment results. Participants will undergo either a standard radical right hemicolectomy or the same surgery combined with indocyanine green fluorescence imaging lymphatic tracer dissection. This imaging technique helps visualize lymphatic structures during surgery for potentially better removal of affected tissue. The study is designed as a prospective, randomized, open, parallel-controlled trial to assess differences between the two approaches. During the study, participants will be monitored for disease-free survival over three years as the primary outcome. Researchers will collect data on clinical outcomes and surgical effectiveness. Patients and their families will be informed about the study and provide consent to participate, with follow-up evaluations conducted to assess the long-term results of the treatments.
CONDITIONS
Official Title
Clinical Study of Radical Right Hemicolectomy Versus Radical Right Hemicolectomy Combined with Indocyanine Green Fluorescence Imaging Lymphatic Tracer Dissection for the Treatment of Right Colon Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 75 years old
- Confirmed adenocarcinoma cancer by pathology
- Tumor located from the cecum to the right third of the transverse colon
- CT showing right colon cancer stage T1-T4a N+ M0
- ASA scores I to III
- ECOG performance status of 0 or 1
- Patient or family member able to understand the study and willing to provide written consent
You will not qualify if you...
- Multiple primary colon cancers occurring at the same or different times
- Intestinal obstruction, perforation, or bleeding requiring emergency surgery
- Not suitable for laparoscopic surgery (e.g., due to extensive abdominal adhesions or inability to tolerate pneumoperitoneum)
- Pregnant or breastfeeding women
- History of serious mental illness
- History of iodine allergy
- Other malignant diseases within the last five years
- Prior neoadjuvant chemotherapy or radiation therapy
- Unstable angina or heart attack within the last 6 months
- Continuous systemic corticosteroid use within one month
AI-Screening
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Trial Site Locations
Total: 1 location
1
The Sixth Affiliated Hospital, Sun Yat-sen University
Guangzhou, China
Actively Recruiting
Research Team
Y
Yanhong Deng, doctor
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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