Actively Recruiting
The Clinical Study of SHR-9839 for Injection in Patients With Advanced Solid Tumors
Led by Shanghai Hengrui Pharmaceutical Co., Ltd. · Updated on 2025-08-11
174
Participants Needed
1
Research Sites
158 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is an open-label, phase I clinical trial of SHR-9839 in patients with advanced solid tumors. The whole study is divided into three stages: dose escalation, dose expansion and efficacy expansion.
CONDITIONS
Official Title
The Clinical Study of SHR-9839 for Injection in Patients With Advanced Solid Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with confirmed unresectable locally advanced or metastatic solid tumors relapsed or refractory to standard treatment, or without applicable standard treatment
- At least one measurable tumor lesion per RECIST v1.1
- ECOG performance status of 0 or 1
- Life expectancy of 12 weeks or more
- Adequate bone marrow and organ function
- Voluntary agreement to participate and signed informed consent
You will not qualify if you...
- Active central nervous system or meningeal metastases
- Anti-tumor treatment (chemotherapy, biotherapy, targeted therapy, immunotherapy, radical radiotherapy, or other clinical research treatments) within 4 weeks before first dose
- History of serious cardiovascular or cerebrovascular diseases
- Radiation therapy over 30Gy within 4 weeks before first dose, or 30Gy or less of palliative radiation within 7 days before first dose
- Previous anti-tumor treatment adverse reactions not recovered to Grade 1 or less per NCI-CTCAE v5.0
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Zhejiang Tumor Hospital
Hangzhou, Zhejiang, China, 310006
Actively Recruiting
Research Team
R
Rongfu Mao, MD
CONTACT
J
Jin Wang, COD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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