Actively Recruiting

Phase 1
Age: 18Years +
All Genders
NCT06484777

A Clinical Study of SHR-9539 in Patients With Multiple Myeloma

Led by Suzhou Suncadia Biopharmaceuticals Co., Ltd. · Updated on 2026-04-16

138

Participants Needed

1

Research Sites

155 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is a multicenter, open-label, dose-escalation/dose-expansion clinical Phase I trial designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy profile of SHR-9539 Injection in patients with multiple myeloma.

CONDITIONS

Official Title

A Clinical Study of SHR-9539 in Patients With Multiple Myeloma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older at the time of informed consent
  • Performance status of 0 or 1 on the Eastern Cooperative Oncology Group (ECOG) scale
  • Confirmed diagnosis of multiple myeloma according to IMWG criteria
  • Life expectancy of at least 3 months
  • Agree to use effective contraception during the study and for 3 months after last drug dose, with negative pregnancy test at screening
Not Eligible

You will not qualify if you...

  • Central nervous system involvement of multiple myeloma
  • Diagnosis of amyloidosis, plasma cell leukemia, Wahl's macroglobulinemia, or POEMS syndrome
  • Prior Grade 3 or higher cytokine release syndrome related to any T cell redirection therapy
  • Other serious illnesses, psychiatric conditions, or social/family factors that may affect safety or study compliance as determined by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

West China Hospital of Sichuan University

Chengdu, Sichuan, China, 610000

Actively Recruiting

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Research Team

Y

Yang Wu

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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A Clinical Study of SHR-9539 in Patients With Multiple Myeloma | DecenTrialz