Study Comparing Single-Incision and Conventional Laparoscopic Gallbladder Removal for Acute Cholecystitis in Adults Aged 18 to 70

What this Trial Is About

Gallstone disease is common in China, affecting about 15% of the population, with 210 million people affected. Acute cholecystitis, a sudden inflammation of the gallbladder often caused by gallstones, can lead to serious complications such as gallbladder perforation and high mortality if untreated. This study investigates the effects of single-incision laparoscopic cholecystectomy SILC compared to conventional laparoscopic cholecystectomy CLC on patient outcomes after surgery for acute cholecystitis, aiming to improve quality of life and reduce pain and scarring. The trial compares two surgical methods SILC, which uses a single incision through the navel, and CLC, which involves three or four small incisions. Both groups may switch to open cholecystectomy if the surgery is difficult to complete. The study is randomized and triple-blinded to ensure unbiased results. Researchers want to establish a standardized procedure for SILC in treating acute cholecystitis and evaluate its safety and impact on postoperative recovery. Participants will be followed for three years to assess the time it takes to return to normal life, the cosmetic results of surgery, postoperative pain, scar quality, and any complications. The study includes regular monitoring and evaluation to measure these outcomes and ensure participant safety. This long-term follow-up will provide valuable information on the effectiveness and patient experience with SILC compared to traditional laparoscopic surgery.

Clinical Study of Single Incision Laparoscopic Cholecystectomy in the Treatment of Patients With Acute Cholecystitis