Actively Recruiting

Phase 1
Phase 2
Age: 18Years +
All Genders
NCT06214156

A Clinical Study of T3011 in Subjects With Advanced Melanoma

Led by Shanghai Pharmaceuticals Holding Co., Ltd · Updated on 2026-01-14

42

Participants Needed

7

Research Sites

139 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This clinical study evaluated the tolerability, safety and preliminary efficacy of T3011 in subjects with advanced melanoma.

CONDITIONS

Official Title

A Clinical Study of T3011 in Subjects With Advanced Melanoma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have advanced melanoma
  • Have at least one measurable tumor lesion
  • Have an ECOG performance status of 0 or 1
  • Expected survival longer than 12 weeks
  • Meet laboratory test requirements
  • For women who can become pregnant, have a negative pregnancy test within 7 days before first dose and agree to use effective contraception until 6 months after last dose
  • For men who can father children, agree to use effective contraception and not donate sperm from consent until 6 months after last dose
  • Understand and voluntarily sign informed consent and agree to comply with study requirements
Not Eligible

You will not qualify if you...

  • Received other antitumor therapy within the specified time before first dose
  • History of other cancers within the specified time before study treatment
  • History or signs of high-risk cardiovascular disease at screening
  • Active infection requiring intravenous antibiotics
  • Autoimmune diseases or history of autoimmune diseases
  • Known psychiatric disorders affecting compliance
  • Pleural, pericardial effusion, or ascites needing drainage before treatment or recent drainage
  • Need for systemic treatment with anti-HSV drugs during study
  • Received live or attenuated vaccines recently or plan to during study
  • Received any tumor vaccine in the past
  • Major surgery within specified time before first dose without recovery or planning major surgery during study
  • History of drug, alcohol abuse within 1 year before consent
  • Pregnant, breastfeeding, or planning pregnancy during study
  • Investigator considers participation inappropriate

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 7 locations

1

Beijing Cancer Hospital

Beijing, China

Actively Recruiting

2

The First Affiliated Hospital of Bengbu Medical College

Bengbu, China

Actively Recruiting

3

Jilin Cancer Hospital

Changchun, China

Actively Recruiting

4

Chengdu Shangjin Nanfu Hospital

Chengdu, China

Actively Recruiting

5

Fujian Cancer Hospital

Fuzhou, China

Actively Recruiting

6

The Third People's Hospital of Zhengzhou

Zhengzhou, China

Actively Recruiting

7

Sun Yat-sen University Cancer Center

Zhongshan, China

Actively Recruiting

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Research Team

J

Jun Guo

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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