Study Comparing Biportal Endoscopic and Fusion Spine Surgeries for Degenerative Lumbar Spondylolisthesis in Adults Aged 50 to 90

What this Trial Is About

Researchers are evaluating the therapeutic effects of two surgical methods for treating degenerative lumbar spondylolisthesis, a condition causing chronic back pain and nerve issues. The study compares dual-channel endoscopic spinal decompression with lumbar decompression combined with fusion, aiming to measure differences in pain relief, neurological improvement, and surgical complication rates. This prospective cohort study involves patients selecting their preferred surgery after being informed about both options. Patients undergo thorough preoperative assessments including pain and neurological function evaluations using tools like the Visual Analogue Scale VAS, JOA score, and ODI score, along with MRI and CT imaging. Surgical details such as operative images, duration, blood loss, and complications are recorded. Tissue samples are collected during surgery for detailed laboratory analysis. Postoperative follow-ups occur at 1, 3, 6, 12, 24, and 36 months to monitor recovery, repeat evaluations, imaging reviews, and complication documentation. Participants provide baseline symptom data and undergo regular evaluations throughout the study period, which lasts up to 36 months after surgery. Researchers analyze collected data statistically to compare the two surgical techniques on pain, neurological function, and imaging results. The study aims to provide detailed insight into the efficacy and safety of these treatments for lumbar degenerative spondylolisthesis.

Clinical Study on the Therapeutic Efficacy of Biportal Endoscopic Decompression Spine Surgery and Lumbar Decompression Fusion Surgery in the Treatment of Degenerative Lumbar Spondylolisthesis