Actively Recruiting
Clinical Study on the Therapeutic Efficacy of Biportal Endoscopic Decompression Spine Surgery and Lumbar Decompression Fusion Surgery in the Treatment of Degenerative Lumbar Spondylolisthesis
Led by The Fourth Affiliated Hospital of Zhejiang University School of Medicine · Updated on 2025-12-17
100
Participants Needed
1
Research Sites
237 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to systematically evaluate the therapeutic efficacy of dual-channel endoscopic spinal decompression versus lumbar decompression with fusion for degenerative lumbar spondylolisthesis. Patients undergoing either procedure will undergo detailed preoperative and postoperative follow-up to compare outcomes between the two techniques, specifically assessing postoperative pain relief, neurological improvement, and the incidence of surgical complications.
CONDITIONS
Official Title
Clinical Study on the Therapeutic Efficacy of Biportal Endoscopic Decompression Spine Surgery and Lumbar Decompression Fusion Surgery in the Treatment of Degenerative Lumbar Spondylolisthesis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 50 and 90 years old with a confirmed diagnosis of degenerative lumbar spondylolisthesis
- Clinical symptoms include chronic pain, nerve compression, or motor dysfunction, confirmed by imaging studies (e.g., MRI or CT)
- No significant improvement after at least 3 months of conservative treatment (e.g., medication, physical therapy), meeting surgical indications
- Understand and consent to the relevant procedures of this study, and sign the informed consent form
You will not qualify if you...
- Patients exhibiting acute spinal cord compression symptoms or requiring urgent surgical intervention
- Patients with a history of spinal surgery or conditions such as spinal deformities, severe osteoporosis, or active infections that may compromise surgical outcomes
- Patients with severe comorbidities affecting assessment, such as cardiovascular disease, liver or kidney failure, or uncontrolled diabetes
- Patients with psychiatric disorders or cognitive impairments preventing understanding or cooperation with the study process
- Patients with allergies to anesthetics or surgical equipment that may increase intraoperative risks
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
4th Affiliated Hospital, School of Medicine, Zhejiang University
Yiwu, Zhejiang, China, 322000
Actively Recruiting
Research Team
X
xiang xue, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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