Actively Recruiting

Phase 2
Age: 18Years - 75Years
All Genders
NCT07205536

Clinical Study of Thiopegfilgrastim for Preventing Bone Marrow Suppression in Thoracic Tumor Chemoradiotherapy

Led by Affiliated Hospital of Nantong University · Updated on 2025-12-11

30

Participants Needed

1

Research Sites

121 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a prospective observational study designed to observe and evaluate the safety and efficacy of mecapegfilgrastim in the treatment of moderate-to-severe myelosuppression associated with concurrent chemoradiotherapy. The project will provide more robust evidence-based medical support for the use of long-acting granulocyte-stimulating agents in patients undergoing concurrent chemoradiotherapy.

CONDITIONS

Official Title

Clinical Study of Thiopegfilgrastim for Preventing Bone Marrow Suppression in Thoracic Tumor Chemoradiotherapy

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 18 to 75 years at the time of informed consent, both sexes eligible
  • Histologically or cytologically confirmed thoracic tumor (esophageal or lung cancer)
  • Investigator judges patient suitable for treatment with mecapegfilgrastim or leucogen tablets
  • Expected survival greater than 3 months
  • Signed informed consent and willingness to comply with study visits
  • Indicated for concurrent chemoradiotherapy and receiving or will receive chemotherapy with high or intermediate risk of febrile neutropenia plus additional risk factors
Not Eligible

You will not qualify if you...

  • Pregnant or lactating women
  • Known allergy to mecapegfilgrastim, pegylated or non-pegylated rhG-CSF, or E. coli-derived products
  • Severe comorbidities compromising patient safety or study completion
  • Any other condition interfering with study conduct or result interpretation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Affiliated Hospital of Nantong University

Nantong, Jiangsu, China, 226001

Actively Recruiting

Loading map...

Research Team

Z

Zhiming CHEN

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here