Actively Recruiting
Clinical Study on the Treatment of Stable Bronchiectasis With Bailing Capsules Combined With Guben Kechuan Granules
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2025-08-11
214
Participants Needed
5
Research Sites
128 weeks
Total Duration
On this page
Sponsors
S
Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead Sponsor
Z
ZhuZhou Central Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if Bailing Capsules in combination Guben Kechuan Granules works to treat stable bronchiectasis in adults.It will also learn about the safety of Bailing Capsules in combination Guben Kechuan Granules The main questions it aims to answer are: Does Bailing Capsules in combination Guben Kechuan Granules lower the number of acute exacerbation in patients with stable bronchiectasis? The safety of the combination of Bailing Capsules and Guben Kechuan Granules ? Researchers will compare the combination of Bailing Capsules and Guben Kechuan Granules to standard Western medical treatment to see if them works to treat stable bronchiectasis. Participants will: Take Bailing Capsules orally (four capsules each time, three times a day) and Guben Kechuan Granules ( three times a day, 1 bag each time )on the basis of standard Western medical treatment or only standard Western medical treatment for 24 weeks Visit the clinic for checkups and tests on 4, 12, 24, 48 weeks Keep a diary of their symptoms
CONDITIONS
Official Title
Clinical Study on the Treatment of Stable Bronchiectasis With Bailing Capsules Combined With Guben Kechuan Granules
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 80 years, any gender
- Diagnosed with bronchiectasis according to Western medical standards
- No acute exacerbation or respiratory infection in the past 4 weeks
- At least two documented acute exacerbations in the past year
- Able to perform pulmonary function tests showing airflow limitation (FEV1/FVC ratio <70%)
- Willing to participate and sign the informed consent form
You will not qualify if you...
- Dry bronchiectasis mainly with hemoptysis
- Bronchiectasis caused by cystic fibrosis or allergic bronchopulmonary aspergillosis
- Other respiratory diseases such as asthma, lung cancer, active tuberculosis, interstitial lung disease, pulmonary thromboembolism, or severe pneumonia
- Serious diseases of heart, liver, kidneys, digestive system, or blood system (e.g., severe hepatitis, liver failure, cirrhosis, acute renal failure, heart failure, gastric perforation, gastrointestinal bleeding, cancers, acute leukemia, aplastic anemia)
- Abnormal liver function with total bilirubin > 1.5× upper limit of normal; ALT > 3× ULN; AST > 3× ULN
- Unable to swallow the study drug
- Known allergy to the test drug
- Participation in other clinical trials or use of investigational drugs/devices within 30 days before randomization
- Women or men of childbearing age unwilling to use contraception during the study
- Pregnant or breastfeeding women
- History of alcohol or drug abuse in the past year
- Use of other traditional Chinese medicine treatments within 7 days before and during the study
- Any other conditions deemed unsuitable by the researcher
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 5 locations
1
The Second Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310000
Actively Recruiting
2
Huzhou Central Hospital
Huzhou, Zhejiang, China, 313000
Not Yet Recruiting
3
Jinhua Central Hospital
Jinhua, Zhejiang, China, 321000
Not Yet Recruiting
4
Yueqing People's Hospital
Yueqing, Zhejiang, China, 325600
Not Yet Recruiting
5
Zhoushan Hospital
Zhoushan, Zhejiang, China, 316000
Not Yet Recruiting
Research Team
H
Haibin Dai
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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