Actively Recruiting
Clinical Study on the Treatment of Stable Bronchiectasis With Bailing Capsules Combined With Guben Kechuan Granules
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2025-08-11
214
Participants Needed
5
Research Sites
8 weeks
Total Duration
On this page
Sponsors
S
Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead Sponsor
Z
ZhuZhou Central Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating whether the combination of Bailing Capsules and Guben Kechuan Granules can help treat adults with stable bronchiectasis. This study also aims to determine the safety of these combined treatments compared to the standard Western medical treatment. The main questions focus on whether this combination reduces the number of acute exacerbations in patients with stable bronchiectasis. Participants in the experimental group will take Bailing Capsules orally (four capsules three times a day) plus Guben Kechuan Granules (one bag three times a day) alongside standard Western medical treatment for 24 weeks. The control group will receive only the standard Western medical treatment. Both groups will be monitored throughout the study period, which includes visits at weeks 4, 12, 24, and 48, with symptom diaries kept by participants. During the study, participants will visit the clinic for checkups and tests to assess lung function at 12, 24, and 48 weeks. Researchers will measure the number of acute exacerbations during treatment and follow-up periods at 24 and 48 weeks. Safety and treatment adherence will be monitored throughout the trial, which lasts for nearly a year, allowing a comprehensive evaluation of treatment effects and patient health.
CONDITIONS
Brief Title
Clinical Study on the Treatment of Stable Bronchiectasis With Bailing Capsules Combined With Guben Kechuan Granules
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 80 years
- Confirmed diagnosis of bronchiectasis by Western medical criteria
- No acute exacerbation or respiratory infection in the past 4 weeks
- At least two documented acute exacerbations in the past year
- Able to perform pulmonary function tests with evidence of airflow limitation
- Willingness to participate and sign informed consent
You will not qualify if you...
- Dry bronchiectasis mainly with hemoptysis
- Bronchiectasis caused by cystic fibrosis or allergic bronchopulmonary aspergillosis
- Other respiratory diseases like asthma, lung cancer, active tuberculosis, interstitial lung disease, pulmonary thromboembolism, or severe pneumonia
- Serious heart, liver, kidney, digestive, or blood diseases as judged by researchers
- Abnormal liver function exceeding specified limits
- Inability to swallow the study drug
- Known allergy to the study drug
- Participation in other clinical trials or use of other research drugs/devices within 30 days before randomization
- Refusal to use contraceptive measures during the study if of childbearing age
- Pregnant or breastfeeding women
- History of alcohol or drug abuse within the past year
- Use of other traditional Chinese medicine treatments within 7 days before or during the study
- Other factors deemed unsuitable by the researcher
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 48 weeks
Participants receive Bailing Capsules combined with Guben Kechuan Granules along with standard Western medical treatment, or standard Western medical treatment alone.
Visits at 12, 24, and 48 weeks for pulmonary function assessments
Trial Site Locations
Total: 5 locations
1
The Second Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310000
Actively Recruiting
2
Huzhou Central Hospital
Huzhou, Zhejiang, China, 313000
Not Yet Recruiting
3
Jinhua Central Hospital
Jinhua, Zhejiang, China, 321000
Not Yet Recruiting
4
Yueqing People's Hospital
Yueqing, Zhejiang, China, 325600
Not Yet Recruiting
5
Zhoushan Hospital
Zhoushan, Zhejiang, China, 316000
Not Yet Recruiting
Research Team
H
Haibin Dai
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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