Actively Recruiting
Clinical Study of TROP-2 PET/CT for Noninvasive Diagnosis of Solid Tumors
Led by Huashan Hospital · Updated on 2024-06-18
60
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will investigate the safety and preliminary diagnostic efficacy of \[68Ga\]Ga-NOTA-T4 or \[18F\]AlF-RESCA-T4 in pancreatic cancer, breast cancer, head and neck cancer, lung cancers and other types of solid tumors. Then, this study will provide a new method for the noninvasive target-specific diagnosis of pancreatic cancer, breast cancer, head and neck cancer, lung cancers and other types of solid tumors. PET imaging of TROP-2 will be integrated to TROP-2-targeted therapies in some of the included patients. Therefore, PET imaging with \[68Ga\]Ga-NOTA-T4 or \[18F\]AlF-RESCA-T4 will help select patients for targeted therapy and monitor treatment responses after the treatment.
CONDITIONS
Official Title
Clinical Study of TROP-2 PET/CT for Noninvasive Diagnosis of Solid Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be between 18 and 65 years of age and of either sex.
- Patients with colorectal cancer confirmed by puncture or surgical pathology.
- Written informed consent signed by the subject or legal guardian or caregiver.
- Willingness and ability to cooperate with all programs of this study.
You will not qualify if you...
- Severe hepatic or renal insufficiency.
- Targeted therapy before radiotherapy or PET/CT scan.
- Renal function: serum creatinine must be less than or equal to the upper limit of the normal range.
- Liver function: bilirubin, AST (SGOT), and ALT (SGPT) must be less than or equal to the upper limit of the normal range.
- History of serious surgery in the last month.
- Participation in other clinical trials during the same period.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Huashan Hospital
Shanghai, China
Actively Recruiting
Research Team
Y
Yihui Guan, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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