Actively Recruiting

Age: 18Years +
All Genders
NCT06571812

A Clinical Study of the TSX Dental Implant System (Xpresso)

Led by ZimVie · Updated on 2026-05-06

62

Participants Needed

2

Research Sites

209 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A prospective, observational, multicenter study where 62 patients needing implants in the maxilla or mandible will be enrolled. The patients will be restored with a final prosthesis no later than 4 months following implant placement surgery. The patients will come back for follow-up evaluations yearly for 2 years.

CONDITIONS

Official Title

A Clinical Study of the TSX Dental Implant System (Xpresso)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients at least 18 years of age
  • Patients planned for dental implant in an edentulous or immediately removed tooth site in the mandible or maxilla
  • Immediate extraction and restoration sites must have intact bony walls (Type I sockets), Type II considered at clinician's discretion
  • Previously extracted sites must be healed at least 3-4 months
  • Presence of opposing dentition allowing functional occlusion is required
  • Implant site must have at least 10mm alveolar bone height and enough space for restoration; minor augmentation allowed
  • Patients must physically tolerate surgical and restorative procedures
  • Signed informed consent provided
  • Agreement to attend evaluations at each study visit
Not Eligible

You will not qualify if you...

  • Known uncontrolled systemic diseases such as diabetes, endocrine disease, heart disease, immuno-compromised status, or mental disorders
  • Current use of bisphosphonates
  • Active infection or severe inflammation at treatment sites
  • Smoking more than 10 cigarettes per day
  • History of therapeutic radiation to head or jaw
  • Pregnant or planning pregnancy within 6 months of enrollment
  • Untreated severe parafunctional habits like bruxism or clenching
  • Previous failed dental implants at intended study site
  • HIV or active Hepatitis infection
  • History of untreated severe generalized periodontitis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Ohio State University

Columbus, Ohio, United States, 43210

Actively Recruiting

2

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104

Active, Not Recruiting

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Research Team

C

Cristina Matthews

CONTACT

H

Hai Bo Wen, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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