Actively Recruiting

Phase Not Applicable
Age: 1Year +
All Genders
NCT05417958

Clinical Trial of Blenderized Tube Feeds Varying in Viscosity

Led by Boston Children's Hospital · Updated on 2026-04-17

40

Participants Needed

1

Research Sites

233 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The investigators are conducting a 16 week multiple cross-over study (N-of-1 trial) comparing two blenderized tube feeds varying in viscosity in 40 children.

CONDITIONS

Official Title

Clinical Trial of Blenderized Tube Feeds Varying in Viscosity

Who Can Participate

Age: 1Year +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age over 1 year
  • Receiving more than 90% of total calories via gastrostomy tube for more than 6 months
  • Gastrostomy tube diameter of at least 14 French
  • Moderate upper gastrointestinal symptoms defined as Gastroparesis Cardinal Symptom Index-Daily Diary composite score over 2
  • Stable gastrointestinal-related medications expected throughout the study
Not Eligible

You will not qualify if you...

  • Diagnosis of cystic fibrosis, primary ciliary dyskinesia, interstitial lung disease, bronchiolitis obliterans, or lung transplant
  • Untreated malabsorptive intestinal diseases such as Crohn's disease or celiac disease
  • History of Nissen fundoplication surgery
  • Use of non-standard enteral formulas for rare metabolic, endocrine, or neurologic diseases
  • Allergy or intolerance to any part of the study diet
  • Inability to tolerate bolus gastric feeds

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Boston Children's Hospital

Boston, Massachusetts, United States, 02115

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

4

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Clinical Trial of Blenderized Tube Feeds Varying in Viscosity | DecenTrialz